Integrated Multimodality Microscopy and Confocal Raman Spectroscopy for In Vivo Skin Evaluation and Diagnosis

Haishan Zeng; Haishan Zeng; Zhenguo Wu; Yunxian Tian; Hequn Wang; Anthony Lee; Jianhua Zhao; Jianhua Zhao; Shuo Tang; David McLean; Sunil Kalia; Harvey Lui; Harvey Lui

doi:10.1364/MICROSCOPY.2018.MW4A.5

Biophotonics Congress: Biomedical Optics Congress 2018 (Microscopy/Translational/Brain/OTS)
OSA Technical Digest (Optica Publishing Group, 2018),
paper MW4A.5
•https://doi.org/10.1364/MICROSCOPY.2018.MW4A.5

Integrated Multimodality Microscopy and Confocal Raman Spectroscopy for In Vivo Skin Evaluation and Diagnosis

Haishan Zeng, Zhenguo Wu, Yunxian Tian, Hequn Wang, Anthony Lee, Jianhua Zhao, Shuo Tang, David McLean, Sunil Kalia, and Harvey Lui

Microscopy Histopathology and Analytics 2018

Hollywood, Florida United States
3–6 April 2018
ISBN: 978-1-943580-41-5

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Confocal and Multimodal Microscopy (MW4A)

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H. Zeng, Z. Wu, Y. Tian, H. Wang, A. Lee, J. Zhao, S. Tang, D. McLean, S. Kalia, and H. Lui, "Integrated Multimodality Microscopy and Confocal Raman Spectroscopy for In Vivo Skin Evaluation and Diagnosis," in Biophotonics Congress: Biomedical Optics Congress 2018 (Microscopy/Translational/Brain/OTS), OSA Technical Digest (Optica Publishing Group, 2018), paper MW4A.5.

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Abstract

We developed an integrated system for label-free in-vivo skin morphology and biochemical analysis. It provides simultaneous, co-registered reflectance confocal microscopy and multiphoton microscopy imaging and performs targeted Raman spectroscopy of interested microstructures under imaging guidance.

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