Longitudinal evaluation of VEGF-induced microvascular changes in skin wounds with large-scale optoacoustic microscopy (LSOM)

Yu-Hang Liu; Yu-Hang Liu; Lorenz M. Brunner; Johannes Rebling; Johannes Rebling; Maya Ben-Yehuda Greenwald; Sabine Werner; Michael Detmar; Daniel Razansky; Daniel Razansky

doi:10.1364/TRANSLATIONAL.2022.JM3A.40

Biophotonics Congress: Biomedical Optics 2022 (Translational, Microscopy, OCT, OTS, BRAIN)
Technical Digest Series (Optica Publishing Group, 2022),
paper JM3A.40
•https://doi.org/10.1364/TRANSLATIONAL.2022.JM3A.40

Longitudinal evaluation of VEGF-induced microvascular changes in skin wounds with large-scale optoacoustic microscopy (LSOM)

Yu-Hang Liu, Lorenz M. Brunner, Johannes Rebling, Maya Ben-Yehuda Greenwald, Sabine Werner, Michael Detmar, and Daniel Razansky

Microscopy Histopathology and Analytics 2022

Fort Lauderdale, Florida United States
24–27 April 2022
ISBN: 978-1-957171-03-6

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Joint Poster Session I On Site (JM3A)

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Y. Liu, L. M. Brunner, J. Rebling, M. B. Greenwald, S. Werner, M. Detmar, and D. Razansky, "Longitudinal evaluation of VEGF-induced microvascular changes in skin wounds with large-scale optoacoustic microscopy (LSOM)," in Biophotonics Congress: Biomedical Optics 2022 (Translational, Microscopy, OCT, OTS, BRAIN), Technical Digest Series (Optica Publishing Group, 2022), paper JM3A.40.

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Abstract

We observed and quantified VEGF-driven enhancement of dermal vascularization in healing wounds by LSOM. The imaging approach can supplement or replace the cumbersome histological procedures to study skin regeneration in its unperturbed in vivo environment.

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