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Statistical Issues Regarding Analyses of Disease-Related Functional Abnormalities

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Abstract

There are many reasons for studying the ways in which visual function changes with disease. One very general reason is to help understand how the visual system works. More specifically, by testing diseased eyes it may be possible to evaluate the generality of conclusions derived from studies of healthy eyes. This type of evaluation may help reveal implicit assumptions that underlie studies of normally functioning visual systems, which typically are investigated using small-sample designs.

© 1992 Optical Society of America

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