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Highly Sensitive and Reliable Plasmonic Nanoparticle-based Microscopy Method for Quantification of Low Abundance Cell Surface Molecules

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Abstract

A microscopy-based method has been developed for the ultrasensitive quantification of low abundance cell surface molecules. This approach, where bound molecules are enumerated via the binding of plasmonic nanoparticles, enables near single molecule detection sensitivity.

© 2017 Optical Society of America

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