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Polarization Resolved Second Harmonic Generation Imaging of Human Ovarian Cancer Tissues Reveals Macro/Supra Molecular Changes in Collagen Structure

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Abstract

Pixel based polarization-resolved SHG imaging probes changes in macromolecular and supramolecular collagen structure in benign and malignant ovarian tumors. Results show decreased chirality and molecular alignment in high grade ovarian cancers.

© 2017 Optical Society of America

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