Multimodal FACED imaging flow cytometry for correlative single-cell morphological analysis

Gwinky G. K. Yip; Michelle C. K. Lo; Kelvin C. M. Lee; Queenie T. K. Lai; Kenneth K. Y. Wong; Kenneth K. Y. Wong; Kevin K. Tsia; Kevin K. Tsia

doi:10.1364/NTM.2021.NTu1C.5

Biophotonics Congress 2021
OSA Technical Digest (Optica Publishing Group, 2021),
paper NTu1C.5
•https://doi.org/10.1364/NTM.2021.NTu1C.5

Multimodal FACED imaging flow cytometry for correlative single-cell morphological analysis

Gwinky G. K. Yip, Michelle C. K. Lo, Kelvin C. M. Lee, Queenie T. K. Lai, Kenneth K. Y. Wong, and Kevin K. Tsia

Novel Techniques in Microscopy 2021

Washington, DC United States
12–16 April 2021
ISBN: 978-1-943580-85-9

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Phase Microscopy I (NTu1C)

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G. G. K. Yip, M. C. K. Lo, K. C. M. Lee, Q. T. K. Lai, K. K. Y. Wong, and K. K. Tsia, "Multimodal FACED imaging flow cytometry for correlative single-cell morphological analysis," in Biophotonics Congress 2021, C. Boudoux, K. Maitland, C. Hendon, M. Wojtkowski, K. Quinn, M. Schanne-Klein, N. Durr, D. Elson, F. Cichos, L. Oddershede, V. Emiliani, O. Maragò, S. Nic Chormaic, N. Pégard, S. Gibbs, S. Vinogradov, M. Niedre, K. Samkoe, A. Devor, D. Peterka, P. Blinder, and E. Buckley, eds., OSA Technical Digest (Optica Publishing Group, 2021), paper NTu1C.5.

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Abstract

We report a high-throughput multimodal imaging flow cytometer for biophysical and morphological analysis of cell cycle progression at single-cell precision with molecular specificity (at >10,000 cells/sec).

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