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Pre-clinical Validation of Near-Infrared Molecular Imaging Agents and Devices for Intraoperative Guidance

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Abstract

Using a custom-made antibody to target the overexpression of epithelial adhesion molecule (EpCAM), a far-red fluorescent gene reporter, a solid phantom, and a military grade intensified image intensifier, we quantified the performance of near-infrared fluorescence imaging for intraoperative margin detection.

© 2013 Optical Society of America

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