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Drug diffusion in soft self-aligned tissue

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Abstract

Optical polarization microscope observations are presented to describe the diffusion of chiral molecules through self-aligned molecular complexes. Strong discrimination effect is observed due to the coupling of the microscopic diffusion and of the elastic energy of orientational deformation of the host. The roles of chirality (or twisting power) of the dopant, the elasticity and boundary conditions of the host as well as the possible ways of diffusion control are discussed.

© 2015 Optical Society of America

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