1,000-fold Sensitivity Enhancement of Porous Si-based Optical Biosensors for Nucleic Acid and Proteins Detection

Sofia Arshavsky-Graham; Rita Vilneski; Federico Faratore; Moran Bercovici; Moran Bercovici; Ester Segal; Ester Segal

doi:10.1364/OMP.2017.OmM4D.6

Optics in the Life Sciences Congress
OSA Technical Digest (online) (Optica Publishing Group, 2017),
paper OmM4D.6
•https://doi.org/10.1364/OMP.2017.OmM4D.6

1,000-fold Sensitivity Enhancement of Porous Si-based Optical Biosensors for Nucleic Acid and Proteins Detection

Sofia Arshavsky-Graham, Rita Vilneski, Federico Faratore, Moran Bercovici, and Ester Segal

Optical Molecular Probes, Imaging and Drug Delivery 2017

San Diego, California United States
2–5 April 2017
ISBN: 978-1-943580-25-5

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Techniques for in-vivo and in-vitro Imaging (OmM4D)

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S. Arshavsky-Graham, R. Vilneski, F. Faratore, M. Bercovici, and E. Segal, "1,000-fold Sensitivity Enhancement of Porous Si-based Optical Biosensors for Nucleic Acid and Proteins Detection," in Optics in the Life Sciences Congress, OSA Technical Digest (online) (Optica Publishing Group, 2017), paper OmM4D.6.

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Abstract

Integration of porous silicon optical biosensors with electrokinetic focusing allows for highly sensitive label-free detection of target nucleic acids and proteins, showing a 1,000-fold improvement in limit of detection compared to a standard assays.

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