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Optica Publishing Group
  • Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP)
  • The Optical Society (Optica Publishing Group, 2019),
  • paper OW5D.4
  • https://doi.org/10.1364/OMP.2019.OW5D.4

Multiplexed Fluorescence Lifetime in vivo FRET Imaging using a Dark Quencher

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We report the characterization of multiplexed lifetime FRET imaging in biological samples by leveraging the dark quencher IRdye QC-1. QC-1 allows to quantify non-invasively ligand-target engagement of multiple receptors in live animals bearing tumor xenografts.

© 2019 The Author(s)

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