SERS monitoring of drug release in cancer cells by gold-decorated biosilica nanoparticles

Ilaria Rea; Stefano Managò; Chiara Tramontano; Donatella Delle Cave; Gianluigi Zito; Giovanna Chianese; Monica Terracciano; Luca De Stefano; Enza Lonardo; Anna Chiara De Luca

doi:10.1364/OMP.2023.OTu2E.5

Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)
Technical Digest Series (Optica Publishing Group, 2023),
paper OTu2E.5
•https://doi.org/10.1364/OMP.2023.OTu2E.5

SERS monitoring of drug release in cancer cells by gold-decorated biosilica nanoparticles

Ilaria Rea, Stefano Managò, Chiara Tramontano, Donatella Delle Cave, Gianluigi Zito, Giovanna Chianese, Monica Terracciano, Luca De Stefano, Enza Lonardo, and Anna Chiara De Luca

Optical Molecular Probes, Imaging and Drug Delivery 2023

Vancouver, British Columbia Canada
24–27 April 2023
ISBN: 978-1-957171-21-0

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Theranostics and Drug Delivery Strategies (OTu2E)

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I. Rea, S. Managò, C. Tramontano, D. D. Cave, G. Zito, G. Chianese, M. Terracciano, L. De Stefano, E. Lonardo, and A. C. De Luca, "SERS monitoring of drug release in cancer cells by gold-decorated biosilica nanoparticles," in Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN), Technical Digest Series (Optica Publishing Group, 2023), paper OTu2E.5.

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Abstract

We describe a hybrid nanosystem for monitoring the drug release in living cancer cells by SERS. The drug is loaded in gold-decorated porous biosilica nanoparticles. The hybrid nanosystem enables the simultaneous drug delivery and sensing.

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