Expand this Topic clickable element to expand a topic
Skip to content
Optica Publishing Group

Optically-Based Bio-Detection Technologies: Toward a Practical Bio-Sensing Solution

Open Access Open Access

Abstract

There is a compelling national need for a next generation BioWatch system of fully integrated and networked biosensors. Such a system will demand inexpensive and compact, yet robust and reliable front-end trigger sensors capable of performing the detect-to-warn mission. These trigger sensors must then be integrated with a practical sample collection method used to provide analyte for a final confimatory sensor capable of detailed speciation. The final confimatory detection stage is critical in order to ensure a broad spectrum of coverage with minimal false positives. One method for accomplishing this demanding identification goal is through multiplexing. In order to be practical, the total integrated sensor solution must be inexpensive enough for large-scale deployment, use only a modest amount of consumables, and operate with minimal human intervention. In this paper we describe specific optically-based approaches for the development of a high-performance, low-cost trigger sensor, as well as a broad spectrum bio-detection technology capable of accurate species identification. We specifically describe a novel bead-based bio-assay detection technology employing nanoparticles and molecular probes as the confirmatory sensor approach, meeting the demanding criteria described above. Full-text article is not available.

© 2005 Optical Society of America


More Like This
Optical Detection of Bio-Agents

Henryk Temkin
ThB2 Optical Solutions for Homeland and National Security (OSHS) 2005

Toward the Practical Application of Polymeric Optical Interconnection Technology

James T. Yardley, L. Eldada, K. M. T. Stengel, L. W. Shacklette, Chengjiu Wu, and C. Xu
MA.2 Organic Thin Films for Photonic Applications (OTF) 1995

Real-Time Bio-Agents and Pathogens Detection Using Elastic and Inelastic Optical Scattering Spectroscopy Techniques

J. P. Jiang, Michael Morrell, and John Babico
FTuU1 Frontiers in Optics (FiO) 2005

Select as filters


Select Topics Cancel
© Copyright 2024 | Optica Publishing Group. All Rights Reserved