Single Molecule Protein Sizing in Double Nano-hole Optical Tweezers

Skyler Wheaton; Reuven Gordon

doi:10.1364/OTA.2015.OtM3E.5

Optics in the Life Sciences
OSA Technical Digest (online) (Optica Publishing Group, 2015),
paper OtM3E.5
•https://doi.org/10.1364/OTA.2015.OtM3E.5

Single Molecule Protein Sizing in Double Nano-hole Optical Tweezers

Skyler Wheaton and Reuven Gordon

Optical Trapping Applications 2015

Vancouver Canada
12–15 April 2015
ISBN: 978-1-55752-954-1

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Optical Manipulation Fundamentals and Technologies II (OtM3E)

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S. Wheaton and R. Gordon, "Single Molecule Protein Sizing in Double Nano-hole Optical Tweezers," in Optics in the Life Sciences, OSA Technical Digest (online) (Optica Publishing Group, 2015), paper OtM3E.5.

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Abstract

Single proteins are trapped in a double nano-hole optical tweezer and their molecular weight is inferred from analysis of the laser transmission fluctuations.

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