Pretreatment Prediction of Neoadjuvant Chemotherapy Response in HER-2 Positive Breast Cancer Patients Using Diffuse Optical Tomography Imaging

Mirella L. Altoe; Alessandro Marone; Hyun K. Kim; Mariella Tejada; Hanina Hibshoosh; Hua Guo; Katherine D. Crew; Melissa K. Accordino; Meghna Trivedi; Kevin Kalinsky; Dawn L. Hershman; Andreas H. Hielscher; Andreas H. Hielscher; Andreas H. Hielscher

doi:10.1364/OTS.2020.SM2D.2

Biophotonics Congress: Biomedical Optics 2020 (Translational, Microscopy, OCT, OTS, BRAIN)
OSA Technical Digest (Optica Publishing Group, 2020),
paper SM2D.2
•https://doi.org/10.1364/OTS.2020.SM2D.2

Pretreatment Prediction of Neoadjuvant Chemotherapy Response in HER-2 Positive Breast Cancer Patients Using Diffuse Optical Tomography Imaging

Mirella L. Altoe, Alessandro Marone, Hyun K. Kim, Mariella Tejada, Hanina Hibshoosh, Hua Guo, Katherine D. Crew, Melissa K. Accordino, Meghna Trivedi, Kevin Kalinsky, Dawn L. Hershman, and Andreas H. Hielscher

Optical Tomography and Spectroscopy 2020

Washington, DC United States
20–23 April 2020
ISBN: 978-1-943580-74-3

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Cancer and Therapy Monitoring with Diffuse Optics and Beyond (SM2D)

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M. L. Altoe, A. Marone, H. K. Kim, M. Tejada, H. Hibshoosh, H. Guo, K. D. Crew, M. K. Accordino, M. Trivedi, K. Kalinsky, D. L. Hershman, and A. H. Hielscher, "Pretreatment Prediction of Neoadjuvant Chemotherapy Response in HER-2 Positive Breast Cancer Patients Using Diffuse Optical Tomography Imaging," in Biophotonics Congress: Biomedical Optics 2020 (Translational, Microscopy, OCT, OTS, BRAIN), OSA Technical Digest (Optica Publishing Group, 2020), paper SM2D.2.

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Abstract

Normalized ctTHb levels measured prior to neoadjuvant chemotherapy can predict breast cancer response to NAC and potentially be used to improve personalized therapeutic strategies for HER-2 positive tumors.

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