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On-Line Liquid Chromatography Detection by Photon Correlation Spectroscopy

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Abstract

Photon Correlation Spectroscopy has been applied to the routine monitoring of proteins eluting off liquid chromatographic separation systems. The technique has been configured as an on-line, in situ detector capable of remote analyses using fibre optic technology. Analyses of flowing protein samples has been demonstrated and its use in process biochemistry as a quality assurance monitor is discussed.

© 1988 Optical Society of America

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