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Conferences > PIBM > 2017 > W3A > W3A.46

Photo-responsive Nanovehicle for Two Independent Wavelength-Triggered Sequential Release of P-gp shRNA and Doxorubicin to Optimize Synergistic Therapy of Multidrug-resistant Cancer Cells

Ming Wu, Xinyi Lin, and Xiaolong Liu

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Abstract

Earlier release of RNA molecules than drugs is vital but still difficult for overcoming multidrug resistance of cancer cells. Herein, we reported photo-responsive mesoporous silica nanoparticles utilizing two independent light to control their sequential release.

© 2017 Optical Society of America

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