Label-free, Optical Measurements of Brain Morphologies in Alzheimer’s Disease Using Quantitative Phase Imaging

Moosung Lee; Moosung Lee; Eeksung Lee; Eeksung Lee; Eeksung Lee; JaeHwang Jung; JaeHwang Jung; Hyeonseung Yu; Hyeonseung Yu; Kyoohyun Kim; Kyoohyun Kim; Jonghee Yoon; Jonghee Yoon; Shinhwa Lee; Shinhwa Lee; Yong Jeong; Yong Jeong; YongKeun Park; YongKeun Park; YongKeun Park

doi:10.1364/PIBM.2017.W3A.81

International Conference on Photonics and Imaging in Biology and Medicine
(Optica Publishing Group, 2017),
paper W3A.81
•https://doi.org/10.1364/PIBM.2017.W3A.81

Label-free, Optical Measurements of Brain Morphologies in Alzheimer’s Disease Using Quantitative Phase Imaging

Moosung Lee, Eeksung Lee, JaeHwang Jung, Hyeonseung Yu, Kyoohyun Kim, Jonghee Yoon, Shinhwa Lee, Yong Jeong, and YongKeun Park

International Conference on Photonics and Imaging in Biology and Medicine 2017

Suzhou China
26–28 September 2017
ISBN: 978-1-943580-35-4

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M. Lee, E. Lee, J. Jung, H. Yu, K. Kim, J. Yoon, S. Lee, Y. Jeong, and Y. Park, "Label-free, Optical Measurements of Brain Morphologies in Alzheimer’s Disease Using Quantitative Phase Imaging," in International Conference on Photonics and Imaging in Biology and Medicine, (Optica Publishing Group, 2017), paper W3A.81.

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Abstract

We employ quantitative phase microscopy technique to investigate structural alterations in brains due to Alzheimer’s disease. Quantifying optical scattering parameters, we show that Alzheimer’s disease is associated with the morphological inhomogeneity of brains.

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