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Plasmonic Sandwich Immunoassay on Fiber Optic Sensor: Sensitivity Enhancement using Refractive Index Media

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Abstract

LSPR properties of bioconjugated gold nanoparticles are exploited in realizing evanescent wave absorbance based fiber optic sandwich immunosensor. In addition, a method to amplify the sensor response by about 2-5 times by using high refractive index medium around nanoparticle labels is demonstrated.

© 2014 Optical Society of America

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