A Monolithic Lab-on-a-Chip for Real Time Liquid Spectroscopy

Borislav Hinkov; Florian Pilat; Laurin Lux; Patricia L. Souza; Patricia L. Souza; Mauro David; Andreas Schwaighofer; Bettina Baumgartner; Bettina Baumgartner; Daniela Ristanić; Benedikt Schwarz; Hermann Detz; Hermann Detz; Aaron M. Andrews; Bernhard Lendl; Gottfried Strasser

doi:10.1364/SENSORS.2022.STu5C.5

Optical Sensors and Sensing Congress 2022 (AIS, LACSEA, Sensors, ES)
Technical Digest Series (Optica Publishing Group, 2022),
paper STu5C.5
•https://doi.org/10.1364/SENSORS.2022.STu5C.5

A Monolithic Lab-on-a-Chip for Real Time Liquid Spectroscopy

Borislav Hinkov, Florian Pilat, Laurin Lux, Patricia L. Souza, Mauro David, Andreas Schwaighofer, Bettina Baumgartner, Daniela Ristanić, Benedikt Schwarz, Hermann Detz, Aaron M. Andrews, Bernhard Lendl, and Gottfried Strasser

Optical Sensors 2022

Vancouver, British Columbia Canada
11–15 July 2022
ISBN: 978-1-957171-10-4

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Point of Care and Compact Biosensors (STu5C)

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B. Hinkov, F. Pilat, L. Lux, P. L. Souza, M. David, A. Schwaighofer, B. Baumgartner, D. Ristanić, B. Schwarz, H. Detz, A. M. Andrews, B. Lendl, and G. Strasser, "A Monolithic Lab-on-a-Chip for Real Time Liquid Spectroscopy," in Optical Sensors and Sensing Congress 2022 (AIS, LACSEA, Sensors, ES), Technical Digest Series (Optica Publishing Group, 2022), paper STu5C.5.

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Abstract

We present a monolithic mid-infrared lab-on-a-chip for sensitive and selective real-time liquid spectroscopy. Beyond state-of-the-art operation of our fingertip-sized devices is demonstrated by in-situ reaction-monitoring of thermally-induced protein-conformational changes and by dynamical residual-water analysis in solvents.

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