Relationship between tissue redox potentials and hemoglobin oxygenation based on fluorescence of NADH / FAD and absorption spectroscopy of oxy / deoxy hemoglobin

Nimmi Ramanujam; Yanping Li; Britton Chance; Douglas Heintzelman; Rebecca Richards-Kortum; Sharon Thomsen; Anita Mahadevan-Jansen

doi:10.1364/AOIPM.1998.JWA2

Biomedical Optical Spectroscopy and Diagnostics / Therapeutic Laser Applications
OSA Trends in Optics and Photonics Series (Optica Publishing Group, 1998),
paper JWA2
•https://doi.org/10.1364/AOIPM.1998.JWA2

Relationship between tissue redox potentials and hemoglobin oxygenation based on fluorescence of NADH / FAD and absorption spectroscopy of oxy / deoxy hemoglobin

Nimmi Ramanujam, Yanping Li, Britton Chance, Douglas Heintzelman, Rebecca Richards-Kortum, Sharon Thomsen, and Anita Mahadevan-Jansen

Therapeutic Laser Applications 1998

Orlando, Florida United States
ISBN: 1-55752-547-1

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Joint Session on Monitoring of Brain Function and Tissue Oxygentation (JWA)

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N. Ramanujam, Y. Li, B. Chance, D. Heintzelman, R. Richards-Kortum, S. Thomsen, and A. Mahadevan-Jansen, "Relationship between tissue redox potentials and hemoglobin oxygenation based on fluorescence of NADH / FAD and absorption spectroscopy of oxy / deoxy hemoglobin," in Biomedical Optical Spectroscopy and Diagnostics / Therapeutic Laser Applications, E. Sevick-Muraca, J. Izatt, and M. Ediger, eds., Vol. 22 of OSA Trends in Optics and Photonics Series (Optica Publishing Group, 1998), paper JWA2.

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Abstract

Neoplastic changes in tissues are reflected by biochemical (tissue metabolism, blood oxygenation, blood volume) and morphological changes. These changes can be monitored non invasively using fluorescence / reflectance spectroscopy in the ultraviolet / visible spectral regions.

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