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  • Biomedical Optical Spectroscopy and Diagnostics / Therapeutic Laser Applications
  • OSA Trends in Optics and Photonics Series (Optica Publishing Group, 1998),
  • paper TMB2

Laser-generated Stress Waves in Medicine: From Tissue Injury to Drug Delivery

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Abstract

Stress waves are generated by one of the following mechanisms: Optical breakdown, ablation, and rapid heating of an absorbing medium. These three modes of laser interaction with matter allow the investigation of cellular and tissue responses to stress waves under a variety of conditions. Stress waves can kill cells, decrease cell viability, and increase the permeability of the plasma membrane and the stratum comeum. Stress waves can induce deleterious effects during medical procedures of high power lasers or facilitate therapeutic modalities, such as topical drug delivery.

© 1998 Optical Society of America

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