Comparison of spatially and temporally resolved diffuse transillumination measurement systems for extraction of optical properties of scattering media

E. Ortiz-Rascón; N. C. Bruce; J. Garduño-Mejía; R. Carrillo-Torres; J. Hernández-Paredes; M. E. Álvarez-Ramos

doi:10.1364/AO.56.009199

Applied Optics
Vol. 56,
Issue 33,
pp. 9199-9204
(2017)
•https://doi.org/10.1364/AO.56.009199

Comparison of spatially and temporally resolved diffuse transillumination measurement systems for extraction of optical properties of scattering media

E. Ortiz-Rascón, N. C. Bruce, J. Garduño-Mejía, R. Carrillo-Torres, J. Hernández-Paredes, and M. E. Álvarez-Ramos

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E. Ortiz-Rascón, N. C. Bruce, J. Garduño-Mejía, R. Carrillo-Torres, J. Hernández-Paredes, and M. E. Álvarez-Ramos, "Comparison of spatially and temporally resolved diffuse transillumination measurement systems for extraction of optical properties of scattering media," Appl. Opt. 56, 9199-9204 (2017)

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- Medical Optics and Biotechnology
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About this Article
History
- Original Manuscript: July 28, 2017
- Revised Manuscript: October 10, 2017
- Manuscript Accepted: October 18, 2017
- Published: November 14, 2017
Virtual Issues
Virtual Journal for Biomedical Optics Vol. 13, Iss. 1

Abstract

This paper discusses the main differences between two different methods for determining the optical properties of tissue optical phantoms by fitting the spatial and temporal intensity distribution functions to the diffusion approximation theory. The consistency in the values of the optical properties is verified by changing the width of the recipient containing the turbid medium; as the optical properties are an intrinsic value of the scattering medium, independently of the recipient width, the stability in these values for different widths implies a better measurement system for the acquisition of the optical properties. It is shown that the temporal fitting method presents higher stability than the spatial fitting method; this is probably due to the addition of the time of flight parameter into the diffusion theory.

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$d_{i}$	$μ_{s}^{'} (d_{i}) [{mm}^{- 1}]$	$Δ μ_{s}^{'} (d_{i})$ [%]	$μ_{a} (d_{i}) [{mm}^{- 1}]$	$Δ μ_{a} (d_{i})$ [%]
25	$1.006 \pm 0.128$	38.0	$0.01027 \pm 0.00211$	71.5
30	$0.763 \pm 0.042$	4.7	$0.00513 \pm 7.2 \times 10^{- 4}$	14.4
35	$0.650 \pm 0.027$	10.8	$0.00468 \pm 4.8 \times 10^{- 4}$	21.9
50	$0.496 \pm 0.012$	31.9	$0.00387 \pm 2.0 \times 10^{- 4}$	35.4

$d_{i}$	$μ_{s}^{'} (d_{i}) [{mm}^{- 1}]$	$Δ μ_{s}^{'} (d_{i})$ [%]	$μ_{a} (d_{i}) [{mm}^{- 1}]$	$Δ μ_{a} (d_{i})$ [%]
25	$0.429 \pm 0.043$	91.5	$0.01494 \pm 5.2 \times 10^{- 4}$	$> 100$
30	$9.819 \pm 0.334$	94.0	$3.1 \times 10^{- 4} \pm 2.7 \times 10^{- 5}$	92.6
35	$7.791 \pm 0.919$	53.9	$2.6 \times 10^{- 4} \pm 4.8 \times 10^{- 5}$	93.8
50	$2.210 \pm 0.223$	56.3	$0.00128 \pm 1.7 \times 10^{- 4}$	69.5

$d_{i}$	$μ_{s}^{'} (d_{i}) [{mm}^{- 1}]$	$Δ μ_{s}^{'} (d_{i})$ [%]	$μ_{a} (d_{i}) [{mm}^{- 1}]$	$Δ μ_{a} (d_{i})$ [%]
25	$1.006 \pm 0.128$	38.0	$0.01027 \pm 0.00211$	71.5
30	$0.763 \pm 0.042$	4.7	$0.00513 \pm 7.2 \times 10^{- 4}$	14.4
35	$0.650 \pm 0.027$	10.8	$0.00468 \pm 4.8 \times 10^{- 4}$	21.9
50	$0.496 \pm 0.012$	31.9	$0.00387 \pm 2.0 \times 10^{- 4}$	35.4

$d_{i}$	$μ_{s}^{'} (d_{i}) [{mm}^{- 1}]$	$Δ μ_{s}^{'} (d_{i})$ [%]	$μ_{a} (d_{i}) [{mm}^{- 1}]$	$Δ μ_{a} (d_{i})$ [%]
25	$0.429 \pm 0.043$	91.5	$0.01494 \pm 5.2 \times 10^{- 4}$	$> 100$
30	$9.819 \pm 0.334$	94.0	$3.1 \times 10^{- 4} \pm 2.7 \times 10^{- 5}$	92.6
35	$7.791 \pm 0.919$	53.9	$2.6 \times 10^{- 4} \pm 4.8 \times 10^{- 5}$	93.8
50	$2.210 \pm 0.223$	56.3	$0.00128 \pm 1.7 \times 10^{- 4}$	69.5

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Applied Optics