Expand this Topic clickable element to expand a topic
Skip to content
Optica Publishing Group
  • Chinese Optics Letters
  • Vol. 20,
  • Issue 8,
  • pp. 081701-
  • (2022)

A novel needle probe for deeper photoacoustic viscoelasticity measurement

Not Accessible

Your library or personal account may give you access

Abstract

We present for the first time, to the best of our knowledge, a needle probe for photoacoustic viscoelasticity (PAVE) measurements at a depth of 1 cm below the sample surface. The probe uses a gradient index rod lens, encased within a side-facing needle (0.7 mm outer diameter), to direct excitation light (532 nm) and detection light (1325 nm) focused on the sample, collecting and directing the returned detection light in a spectral domain low coherence interferometry system, which allows for obtaining optical phase differences due to photoacoustic oscillations. The feasibility of needle probe for PAVE depth characterization was investigated on gelatin phantoms and in vitro biological tissues. The experimental results in an in vivo animal model predict the great potential of this technique for in vivo tumor boundary detection.

© 2022 Chinese Laser Press

PDF Article
More Like This
Simultaneous optical absorption and viscoelasticity imaging based on photoacoustic lock-in measurement

Yue Zhao, Sihua Yang, Conggui Chen, and Da Xing
Opt. Lett. 39(9) 2565-2568 (2014)

Spectral interferometric depth-resolved photoacoustic viscoelasticity imaging

Shumin Du, Zhongjiang Chen, and Da Xing
Opt. Lett. 46(7) 1724-1727 (2021)

Viscoelasticity imaging of biological tissues with phase-resolved photoacoustic measurement

Guodong Gao, Sihua Yang, and Da Xing
Opt. Lett. 36(17) 3341-3343 (2011)

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Select as filters


Select Topics Cancel
© Copyright 2024 | Optica Publishing Group. All Rights Reserved