Abstract
The analytical solutions for the coupled diffusion equations that are encountered in diffuse fluorescence spectroscopy/imaging for regular geometries were compared with the well-established numerical models, which are based on the finite element method. Comparison among the analytical solutions obtained using zero boundary conditions and extrapolated boundary conditions (EBCs) was also performed. The results reveal that the analytical solutions are in close agreement with the numerical solutions, and solutions obtained using EBCs are more accurate in obtaining the mean time of flight data compared to their counterpart. The analytical solutions were also shown to be capable of providing bulk optical properties through a numerical experiment using a realistic breast model.
© 2013 Optical Society of America
Full Article | PDF ArticleMore Like This
Kalyan Ram Ayyalasomayajula and Phaneendra K. Yalavarthy
J. Opt. Soc. Am. A 30(3) 537-552 (2013)
Aichen Wang, Renfu Lu, and Lijuan Xie
Appl. Opt. 55(1) 95-103 (2016)
David Hattery, Victor Chernomordik, Murray Loew, Israel Gannot, and Amir Gandjbakhche
J. Opt. Soc. Am. A 18(7) 1523-1530 (2001)