Expand this Topic clickable element to expand a topic
Skip to content
Optica Publishing Group

Specialized synaptic pathway for chromatic signals beneath S-cone photoreceptors is common to human, Old and New World primates

Not Accessible

Your library or personal account may give you access

Abstract

The distribution of the soluble NSF-attachment protein receptor protein syntaxin-4 and the Na-K-Cl cotransporter (NKCC) were investigated in the outer plexiform layer of human retina using immunohistochemistry. Both proteins, which are proposed to be components of a gamma-aminobutyric acid mediated feed-forward circuit from horizontal cells directly to bipolar cells, were enriched beneath S-cones. The expression pattern of syntaxin-4 was further analyzed in baboon and marmoset to determine if the synaptic specialization is common to primates. Syntaxin-4 was enriched beneath S-cones in both species, which together with the human results indicates that this specialization may have evolved for the purpose of mediating unique color vision capacities that are exclusive to primates.

© 2014 Optical Society of America

Full Article  |  PDF Article
More Like This
Neurobiological hypothesis of color appearance and hue perception

Brian P. Schmidt, Maureen Neitz, and Jay Neitz
J. Opt. Soc. Am. A 31(4) A195-A207 (2014)

Representation of cone signals in the primate retina

David J. Calkins
J. Opt. Soc. Am. A 17(3) 597-606 (2000)

Cone-isolating ON–OFF electroretinogram for studying chromatic pathways in the retina

James A. Kuchenbecker, Scott H. Greenwald, Maureen Neitz, and Jay Neitz
J. Opt. Soc. Am. A 31(4) A208-A213 (2014)

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Figures (3)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Select as filters


Select Topics Cancel
© Copyright 2024 | Optica Publishing Group. All Rights Reserved