Abstract

We demonstrate a silo-filter (SF) complementary metal-oxide semiconductor (CMOS) image sensor for a chip-scale fluorescence microscope. The extruded pixel design with metal walls between neighboring pixels guides fluorescence emission through the thick absorptive filter to the photodiode of a pixel. Our prototype device achieves 13 μm resolution over a wide field of view ($4.8\mathrm{mm}\times 4.4\mathrm{mm}$). We demonstrate bright-field and fluorescence longitudinal imaging of living cells in a compact, low-cost configuration.

© 2013 Optical Society of America

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