Expand this Topic clickable element to expand a topic
Skip to content
Optica Publishing Group

Photothermal laser speckle imaging

Not Accessible

Your library or personal account may give you access

Abstract

The analysis of speckle contrast in a time-integrated speckle pattern enables visualization of superficial blood flow in exposed vasculature, a method we call laser speckle imaging (LSI). With current methods, LSI does not enable visualization of subsurface or small vasculature, because of optical scattering by stationary structures. In this work we propose a new technique called photothermal LSI to improve the visualization of blood vessels. A 595 nm laser pulse was used to excite blood in both in vitro and in vivo samples. The high absorption coefficient of blood at this wavelength results in efficient conversion of optical energy to thermal energy, resulting in an increase in the local temperature and hence increased scatterer motion, and thus a transient decrease in speckle contrast. As a result, we found that photothermal LSI was able to visualize blood vessels that were hidden when imaged with a conventional LSI system.

© 2014 Optical Society of America

Full Article  |  PDF Article
More Like This
Visualization of in vitro deep blood vessels using principal component analysis based laser speckle imaging

Jose Angel Arias-Cruz, Roger Chiu, Hayde Peregrina-Barreto, Ruben Ramos-Garcia, Teresita Spezzia-Mazzocco, and Julio C. Ramirez-San-Juan
Biomed. Opt. Express 10(4) 2020-2031 (2019)

Simple correction factor for laser speckle imaging of flow dynamics

J. C. Ramirez-San-Juan, R. Ramos-Garcia, G. Martinez-Niconoff, and B. Choi
Opt. Lett. 39(3) 678-681 (2014)

Momentum transfer Monte Carlo for the simulation of laser speckle imaging and its application in the skin

Caitlin Regan, Carole Hayakawa, and Bernard Choi
Biomed. Opt. Express 8(12) 5708-5723 (2017)

Supplementary Material (2)

Media 1: MP4 (266 KB)     
Media 2: MP4 (481 KB)     

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Figures (3)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Select as filters


Select Topics Cancel
© Copyright 2024 | Optica Publishing Group. All Rights Reserved