Abstract
We propose a laser Doppler projection tomography (LDPT) method to obtain visualization of three-dimensional (3D) flowing structures. With LDPT, the flowing signal is extracted by a modified laser Doppler method, and the 3D flowing image is reconstructed by the filtered backprojection algorithm. Phantom experiments are performed to demonstrate that LDPT is able to obtain 3D flowing structure with higher signal-to-noise ratio and spatial resolution. Our experiment results display its potentially useful application to develop 3D label-free optical angiography for the circulation system of live small animal models or microfluidic experiments.
© 2014 Optical Society of America
Full Article | PDF ArticleMore Like This
Guanping Feng, Junbo Chen, Xuanlong Lu, Dingan Han, and Yaguang Zeng
Opt. Lett. 38(15) 2654-2656 (2013)
Hugang Ren, Congwu Du, and Yingtian Pan
Opt. Lett. 37(8) 1388-1390 (2012)
Jiang You, Congwu Du, Nora D. Volkow, and Yingtian Pan
Biomed. Opt. Express 5(9) 3217-3230 (2014)