The Effect of Aberration Correction on Coherent Raman Imaging of Mouse Brain Tissues

Seho Kim; Seho Kim; Jong Min Lim; Seokchan Yoon; Youngjin Choi; Youngjin Choi; Jin Hee Hong; Jin Hee Hong; Wonshik Choi; Wonshik Choi; Minhaeng Cho; Minhaeng Cho

doi:10.1364/3D.2022.JTh2A.6

Imaging and Applied Optics Congress 2022 (3D, AOA, COSI, ISA, pcAOP)
Technical Digest Series (Optica Publishing Group, 2022),
paper JTh2A.6
•https://doi.org/10.1364/3D.2022.JTh2A.6

The Effect of Aberration Correction on Coherent Raman Imaging of Mouse Brain Tissues

Seho Kim, Jong Min Lim, Seokchan Yoon, Youngjin Choi, Jin Hee Hong, Wonshik Choi, and Minhaeng Cho

Propagation Through and Characterization of Atmospheric and Oceanic Phenomena 2022

Vancouver, British Columbia Canada
11–15 July 2022
ISBN: 978-1-957171-09-8

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Joint Poster Session III (On-Site) (JTh2A)

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S. Kim, J. M. Lim, S. Yoon, Y. Choi, J. H. Hong, W. Choi, and M. Cho, "The Effect of Aberration Correction on Coherent Raman Imaging of Mouse Brain Tissues," in Imaging and Applied Optics Congress 2022 (3D, AOA, COSI, ISA, pcAOP), Technical Digest Series (Optica Publishing Group, 2022), paper JTh2A.6.

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Abstract

We observed that coherent Raman imaging signal enhancement by the aberration correction is approximately proportional to the Strehl ratio enhancement, not its third power. The Raman signal originating from out-of-focus planes explains this discrepancy.

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