Abstract

This paper is Part 2 of a three-part sequence dealing with coherent optical signal processing methods for screening Pap smears. Part 2 is devoted to model analysis and evaluation. A mathematical cell model is established to develop the radial spatial frequency profiles of representative cells F(ρ). The quantity ρ²|F(ρ)|² is shown to be most effective in bringing out normal/malignant cell transform differences. Photographic contrast and gamma play a major role in amplifying cell discriminant features and reducing the effects of the aperture contribution.

© 1978 Optical Society of America

Screening of cervical cytological samples using coherent optical processing. Part 1

B. Pernick, R. E. Kopp, J. Lisa, J. Mendelsohn, H. Stone, and R. Wohlers
Appl. Opt. 17(1) 21-34 (1978)

Screening of cervical cytological samples using coherent optical processing. Part 3

B. Pernick, S. Jost, R. Herold, R. E. Kopp, J. Mendelsohn, and R. Wohlers
Appl. Opt. 17(1) 43-51 (1978)

Paraxial analysis of light scattering by biological cells in a flow system

B. J. Pernick, M. R. Wohlers, and J. Mendelsohn
Appl. Opt. 17(20) 3205-3215 (1978)

Fourier optical approach to the extraction of morphological parameters from the diffraction pattern of biological cells

Bernhard Türke, Günter Seger, Manfred Achatz, and Werner v. Seelen
Appl. Opt. 17(17) 2754-2761 (1978)

Bilinear processing of 1-D signals by use of linear 2-D coherent optical processors

Bahaa E. A. Saleh
Appl. Opt. 17(21) 3408-3411 (1978)