We demonstrate that an optical probe beam with high spherical aberration used for glucose concentration measurements gives better sensitivity compared to a probe beam free of aberrations, under similar conditions. We place a singlet focusing lens at a large distance from a laser source with a Gaussian intensity profile to obtain a spherically aberrated probe beam with negligible truncation. The aberrated probe beam propagates through a transparent liquid sample. Intensity profiles of the transmitted beam are recorded by means of a homodyne profiler to perform the glucose concentration measurements accurately.
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