Abstract
Melanoma is a common, highly fatal skin cancer. Photoacoustic imaging can achieve highly sensitive and high-contrast detection of melanin molecules in tissues, also inheriting the high penetration depth and high spatial resolution characteristics of ultrasound imaging, thus it is a very promising non-invasive diagnostic tool for early melanoma. In this work, we built an acoustic-resolution-based photoacoustic microscopy system, using 1064 nm/532 nm pulsed light to observe melanoma in the back of a mouse with simultaneous photoacoustic/ultrasound imaging. Through the fusion of multi-modal images, accurate positioning of melanoma and its surrounding normal tissues were realized. This work will further promote the application of photoacoustic imaging in the clinical diagnosis of early melanoma.
© 2021 Optical Society of America
Full Article | PDF ArticleMore Like This
Yating Wang, Dong Xu, Sihua Yang, and Da Xing
Biomed. Opt. Express 7(2) 279-286 (2016)
Jenny Hult, Aboma Merdasa, Agnes Pekar-Lukacs, Magne Tordengren Stridh, Azin Khodaverdi, John Albinsson, Bodil Gesslein, Ulf Dahlstrand, Linn Engqvist, Yousef Hamid, Douglas Larsson Albèr, Bertil Persson, Tobias Erlöv, Rafi Sheikh, Magnus Cinthio, and Malin Malmsjö
Biomed. Opt. Express 12(7) 4097-4114 (2021)
Magne Tordengren Stridh, Jenny Hult, Aboma Merdasa, John Albinsson, Agnes Pekar-Lukacs, Bodil Gesslein, Ulf Dahlstrand, Karl Engelsberg, Johanna Berggren, Magnus Cinthio, Rafi Sheikh, and Malin Malmsjö
Biomed. Opt. Express 13(1) 410-425 (2022)