Abstract

As an important part of optical-resolution photoacoustic microscopy, the acoustic lens is responsible for efficient collection of photoacoustic signals. The spherical focused acoustic lens is commonly used in photoacoustic microscopy because of its efficient detection of the photoacoustic signal in the focus area. However, the narrow depth of field of the spherical focused acoustic lens limits the expansion of the depth of field of the photoacoustic microscopy. To solve this problem, a Bessel acoustic-beam acoustic lens is proposed. The Bessel acoustic-beam acoustic lens replaces the spherical concave surface with a conical concave surface to generate a Bessel acoustic beam with non-diffraction. Using the simulation model of Bessel acoustic-beam acoustic lens constructed by COMSOL Multiphysics, it is verified theoretically that the Bessel acoustic-beam acoustic lens can improve the depth of field of detection by ${\sim}{2}$ times. The Bessel acoustic-beam acoustic lens can further promote the capability of high-speed and large volumetric imaging of optical-resolution photoacoustic microscopy and will be helpful in the acquisition of physiological and pathological processes.

© 2022 Optica Publishing Group

Virtual optical-resolution photoacoustic microscopy using the k-Wave method

Xianlin Song, Ganyu Chen, Aojie Zhao, Xueyan Liu, and Jiahao Zeng
Appl. Opt. 60(36) 11241-11246 (2021)

Depth-extended acoustic-resolution photoacoustic microscopy based on a two-stage deep learning network

Jing Meng, Xueting Zhang, Liangjian Liu, Silue Zeng, Chihua Fang, and Chengbo Liu
Biomed. Opt. Express 13(8) 4386-4397 (2022)

High-resolution and extended-depth-of-field photoacoustic endomicroscopy by scanning-domain synthesis of optical beams

Xin Jin, Xinkun Wang, Kedi Xiong, and Sihua Yang
Opt. Express 27(14) 19369-19381 (2019)

Fast axial-scanning photoacoustic microscopy using tunable acoustic gradient lens

Xiaoquan Yang, Bowen Jiang, Xianlin Song, Jianshuang Wei, and Qingming Luo
Opt. Express 25(7) 7349-7357 (2017)

Reflection-mode Bessel-beam photoacoustic microscopy for in vivo imaging of cerebral capillaries

Bowen Jiang, Xiaoquan Yang, and Qingming Luo
Opt. Express 24(18) 20167-20176 (2016)