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Optica Publishing Group
  • Applied Spectroscopy
  • Vol. 41,
  • Issue 5,
  • pp. 735-738
  • (1987)

Antibody-Based Fiberoptics Biosensor for the Carcinogen Benzo(a)pyrene

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A new antibody-based fiberoptics biosensor was used to detect the important carcinogen benzo(a)pyrene (BaP). The fiberoptics sensor utilizes anti-BaP antibodies covalently bound to its tip. A helium cadmium laser was used as the excitation source to induce fluorescence from BaP conjugated to the bound anti-BaP antibodies. The fiberoptics device can detect 1 femtomole of BaP in a 5-μL sample drop.

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