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Optica Publishing Group
  • Applied Spectroscopy
  • Vol. 66,
  • Issue 1,
  • pp. 75-81
  • (2012)

Interaction of (−)-Epigallocatechin Gallate and Silver Colloid with Bovine Serum Albumin

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<b>The interaction between borate-ion-stabilized silver (Ag) nanoparticles and (−)-epigallocatechin gallate (EGCG) has been investigated. The added EGCG molecules chelate with the borate ions to form a borate ester. This complex provides a better stability to the metal particles by formation of a cap around them. The spectral line profile of the surface plasmon resonance band of the metal particles has been used to probe the metal-molecule interactions. The withdrawal of electron density from the surface of the Ag particle by the phenolic group of EGCG molecule results in a red-shift of the surface plasmon resonance band of the particles in the sol. In this study we show that both borate-ester-capped Ag nanoparticles and the borate ester itself can be transported by blood plasma serum albumin.</b>

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