Abstract

We report the development of a novel fiber-optic Raman probe using a graded index fluorocarbon optical fiber. The fluorocarbon fiber has a simple Raman spectrum, a low fluorescence background, and generates a Raman signal that in turbid media serves as an intense reference Raman signal that corrects for albedo. The intensity of the reference signal can easily be varied as needed by scaling the length of the excitation fiber. Additionally, the fluorocarbon probe eliminates the broad silica Raman bands generated in conventional silica-core fiber without the need for filters.

Optical Fiber Probe for Biomedical Raman Spectroscopy

Jason T. Motz, Martin Hunter, Luis H. Galindo, Joseph A. Gardecki, John R. Kramer, Ramachandra R. Dasari, and Michael S. Feld
Appl. Opt. 43(3) 542-554 (2004)

Next-generation Raman tomography instrument for non-invasive in vivo bone imaging

Jennifer-Lynn H. Demers, Francis W.L. Esmonde-White, Karen A. Esmonde-White, Michael D. Morris, and Brian W. Pogue
Biomed. Opt. Express 6(3) 793-806 (2015)

Hollow-core photonic crystal fiber-optic probes for Raman spectroscopy

Stanislav O. Konorov, Christopher J. Addison, H. Georg Schulze, Robin F. B. Turner, and Michael W. Blades
Opt. Lett. 31(12) 1911-1913 (2006)

Use of a mechanical iris-based fiber optic probe for spatially offset Raman spectroscopy

Zhiyong Wang, Hao Ding, Guijin Lu, and Xiaohong Bi
Opt. Lett. 39(13) 3790-3793 (2014)

Kagome hollow-core photonic crystal fiber probe for Raman spectroscopy

Petru Ghenuche, Silke Rammler, Nicolas Y. Joly, Michael Scharrer, Michael Frosz, Jérôme Wenger, Philip St. J. Russell, and Hervé Rigneault
Opt. Lett. 37(21) 4371-4373 (2012)