Multimodal quantitative imaging of brain cancer in cultured cells

Xin Feng, Alona Muzikansky, Alonzo H. Ross, Michael R. Hamblin, Peter R. Jermain, and Anna N. Yaroslavsky

Biomed. Opt. Express 10(8), 4237-4248 (2019)  View: HTML | PDF

Anti-inflammatory and cell proliferative effect of the 1270 nm laser irradiation on the BALB/c nude mouse model involves activation of the cell antioxidant system

Dinara Dolgova, Tatiana Abakumova, Tatiana Gening, Ludmila Poludnyakova, Igor Zolotovskii, Dmitrii Stoliarov, Andrei Fotiadi, Anna Khokhlova, Edik Rafailov, and Sergei Sokolovski

Biomed. Opt. Express 10(8), 4261-4275 (2019)  View: HTML | PDF

Attenuation of stripe artifacts in optical coherence tomography images through wavelet-FFT filtering

Robert Byers and Stephen Matcher

Biomed. Opt. Express 10(8), 4179-4189 (2019)  View: HTML | PDF

Polarization-sensitive optical coherence tomography with a conical beam scan for the investigation of birefringence and collagen alignment in the human cervix

Wei Li, Brenda F. Narice, Dilly O. Anumba, and Stephen J. Matcher

Biomed. Opt. Express 10(8), 4190-4206 (2019)  View: HTML | PDF

Analysis of low-scattering regions in optical coherence tomography: applications to neurography and lymphangiography

Valentin Demidov, Lev A. Matveev, Olga Demidova, Alexander L. Matveyev, Vladimir Y. Zaitsev, Costel Flueraru, and I. Alex Vitkin

Biomed. Opt. Express 10(8), 4207-4219 (2019)  View: HTML | PDF

Optical assessment of alterations of microrheologic and microcirculation parameters in cardiovascular diseases

Andrei E. Lugovtsov, Yury I. Gurfinkel, Petr B. Ermolinskiy, Anastasiya I. Maslyanitsina, Larisa I. Dyachuk, and Alexander V. Priezzhev

Biomed. Opt. Express 10(8), 3974-3986 (2019)  View: HTML | PDF  [Suppl. Mat. (3)]

Phenomenon of atypical vascular effects of epinephrine and an increase of photodynamic response by nitroglycerin in rats with colon adenocarcinoma: adrenergic and nitrergic mechanisms and novel applied aspects

Ilana Agranovich, Ekaterina Borisova, Nikita Navolokin, Alla Bucharskaya, Galina Maslyakova, Alexander Shirokov, Arkady Abdurashitov, Ivan Angelov, Alexander Khorovodov, Andrey Terskov, Aysel Mamedova, Maria Klimova, and Oxana Semyachkina-Glushkovskaya

Biomed. Opt. Express 10(8), 4115-4125 (2019)  View: HTML | PDF

Label-free characterization of white blood cells using fluorescence lifetime imaging and flow-cytometry: molecular heterogeneity and erythrophagocytosis [Invited]

Boris P. Yakimov, Maria A. Gogoleva, Alexey N. Semenov, Sergey A. Rodionov, Marina V. Novoselova, Alexey V. Gayer, Alexey V. Kovalev, Alexey I. Bernakevich, Victor V. Fadeev, Artashes G. Armaganov, Vladimir P. Drachev, Dmitry A. Gorin, Maxim E. Darvin, Vladislav I. Shcheslavskiy, Gleb S. Budylin, Alexander V. Priezzhev, and Evgeny A. Shirshin

Biomed. Opt. Express 10(8), 4220-4236 (2019)  View: HTML | PDF

Hybrid organosilicon/polyol phantom for photoacoustic imaging

Fulvio Ratto, Lucia Cavigli, Claudia Borri, Sonia Centi, Giada Magni, Marina Mazzoni, and Roberto Pini

Biomed. Opt. Express 10(8), 3719-3730 (2019)  View: HTML | PDF

Review of micro-optical sectioning tomography (MOST): technology and applications for whole-brain optical imaging [Invited]

Ting Zheng, Zhao Feng, Xiaojun Wang, Tao Jiang, Rui Jin, Peilin Zhao, Ting Luo, Hui Gong, Qingming Luo, and Jing Yuan

Biomed. Opt. Express 10(8), 4075-4096 (2019)  View: HTML | PDF

Novel methodology to image stromal tissue and assess its morphological features with polarized light: towards a tumour microenvironment prognostic signature

Jared Westreich, Mohammadali Khorasani, Blake Jones, Valentin Demidov, Sharon Nofech-Mozes, and Alex Vitkin

Biomed. Opt. Express 10(8), 3963-3973 (2019)  View: HTML | PDF

Diffuse optical tomography of the breast: a potential modifiable biomarker of breast cancer risk with neoadjuvant chemotherapy

Mirella L. Altoe, Alessandro Marone, Hyun K. Kim, Kevin Kalinsky, Dawn L. Hershman, Andreas H. Hielscher, and Richard S. Ha

Biomed. Opt. Express 10(8), 4305-4315 (2019)  View: HTML | PDF

Enhanced resolution 3D digital cytology and pathology with dual-view inverted selective plane illumination microscopy

Bihe Hu, Guang Li, and J. Quincy Brown

Biomed. Opt. Express 10(8), 3833-3846 (2019)  View: HTML | PDF

Denoising of stimulated Raman scattering microscopy images via deep learning

Bryce Manifold, Elena Thomas, Andrew T. Francis, Andrew H. Hill, and Dan Fu

Biomed. Opt. Express 10(8), 3860-3874 (2019)  View: HTML | PDF

Identifying crossing collagen fibers in human corneal tissues using pSHG images

M. Alizadeh, D. Merino, G. Lombardo, M. Lombardo, R. Mencucci, M. Ghotbi, and P. Loza-Alvarez

Biomed. Opt. Express 10(8), 3875-3888 (2019)  View: HTML | PDF

Elimination of imaging artifacts in second harmonic generation microscopy using interferometry

Maxime Pinsard, Margaux Schmeltz, Jarno van der Kolk, Shunmoogum A Patten, Heide Ibrahim, Lora Ramunno, Marie-Claire Schanne-Klein, and François Légaré

Biomed. Opt. Express 10(8), 3938-3952 (2019)  View: HTML | PDF  [Suppl. Mat. (2)]

Comparison of nonlinear microscopy and frozen section histology for imaging of Mohs surgical margins

Michael G. Giacomelli, Beverly E. Faulkner-Jones, Lucas C. Cahill, Tadayuki Yoshitake, Daihung Do, and James G. Fujimoto

Biomed. Opt. Express 10(8), 4249-4260 (2019)  View: HTML | PDF

Volumetric stimulated Raman scattering imaging of cleared tissues towards three-dimensional chemical histopathology

Junjie Li, Peng Lin, Yuying Tan, and Ji-Xin Cheng

Biomed. Opt. Express 10(8), 4329-4339 (2019)  View: HTML | PDF  [Suppl. Mat. (12)]

Deriving external forces via convolutional neural networks for biomedical image segmentation

Yibiao Rong, Dehui Xiang, Weifang Zhu, Fei Shi, Enting Gao, Zhun Fan, and Xinjian Chen

Biomed. Opt. Express 10(8), 3800-3814 (2019)  View: HTML | PDF

No-search focus prediction at the single cell level in digital holographic imaging with deep convolutional neural network

Keyvan Jaferzadeh, Seung-Hyeon Hwang, Inkyu Moon, and Bahram Javidi

Biomed. Opt. Express 10(8), 4276-4289 (2019)  View: HTML | PDF  [Suppl. Mat. (2)]

Optofluidic microcapillary biosensor for label-free, low glucose concentration detection

Hongdan Wan, Jijing Chen, Cheng Wan, Quan Zhou, Jie Wang, and Zuxing Zhang

Biomed. Opt. Express 10(8), 3929-3937 (2019)  View: HTML | PDF

Multi-phase level set algorithm based on fully convolutional networks (FCN-MLS) for retinal layer segmentation in SD-OCT images with central serous chorioretinopathy (CSC)

Yanan Ruan, Jie Xue, Tianlai Li, Danhua Liu, Hua Lu, Meirong Chen, Tingting Liu, Sijie Niu, and Dengwang Li

Biomed. Opt. Express 10(8), 3987-4002 (2019)  View: HTML | PDF

Pilot study of transcranial photobiomodulation of lymphatic clearance of beta-amyloid from the mouse brain: breakthrough strategies for non-pharmacologic therapy of Alzheimer’s disease

Ekaterina Zinchenko, Nikita Navolokin, Alexander Shirokov, Boris Khlebtsov, Alexander Dubrovsky, Elena Saranceva, Arkady Abdurashitov, Alexander Khorovodov, Andrey Terskov, Aysel Mamedova, Maria Klimova, Ilana Agranovich, Dmitry Martinov, Valery Tuchin, Oxana Semyachkina-Glushkovskaya, and Jurgen Kurts

Biomed. Opt. Express 10(8), 4003-4017 (2019)  View: HTML | PDF

Automatic identification and characterization of the epiretinal membrane in OCT images

Sergio Baamonde, Joaquim de Moura, Jorge Novo, Pablo Charlón, and Marcos Ortega

Biomed. Opt. Express 10(8), 4018-4033 (2019)  View: HTML | PDF

Handheld probe for quantitative micro-elastography

Qi Fang, Brooke Krajancich, Lixin Chin, Renate Zilkens, Andrea Curatolo, Luke Frewer, James D. Anstie, Philip Wijesinghe, Colin Hall, Benjamin F. Dessauvagie, Bruce Latham, Christobel M. Saunders, and Brendan F. Kennedy

Biomed. Opt. Express 10(8), 4034-4049 (2019)  View: HTML | PDF

Automated segmentation of peripapillary retinal boundaries in OCT combining a convolutional neural network and a multi-weights graph search

Pengxiao Zang, Jie Wang, Tristan T. Hormel, Liang Liu, David Huang, and Yali Jia

Biomed. Opt. Express 10(8), 4340-4352 (2019)  View: HTML | PDF

Cerebral oximetry performance testing with a 3D-printed vascular array phantom

Ali Afshari, Pejman Ghassemi, Jonathan Lin, Molly Halprin, Jianting Wang, Gonzalo Mendoza, Sandy Weininger, and T. Joshua Pfefer

Biomed. Opt. Express 10(8), 3731-3746 (2019)  View: HTML | PDF

Spectroscopic signature of the pathological processes of carious dentine based on FTIR investigations of the oral biological fluids

Pavel Seredin, Dmitry Goloshchapov, Yuri Ippolitov, and Jitraporn Vongsvivut

Biomed. Opt. Express 10(8), 4050-4058 (2019)  View: HTML | PDF

Robust quantitative single-exposure laser speckle imaging with true flow speckle contrast in the temporal and spatial domains

Chenge Wang, Zili Cao, Xin Jin, Weihao Lin, Yang Zheng, Bixin Zeng, and M. Xu

Biomed. Opt. Express 10(8), 4097-4114 (2019)  View: HTML | PDF

Dual-band refractometric terahertz biosensing with intense wave-matter-overlap microfluidic channel

Feng Lan, Feng Luo, Pinaki Mazumder, Ziqiang Yang, Lin Meng, Zhengqiang Bao, Jun Zhou, Yaxin Zhang, Shixiong Liang, Zongjun Shi, Abdur Rauf Khan, Ziqi Zhang, Luyang Wang, Jing Yin, and Hongxin Zeng

Biomed. Opt. Express 10(8), 3789-3799 (2019)  View: HTML | PDF

Study of in vivo brain glioma in a mouse model using continuous-wave terahertz reflection imaging

Limin Wu, Degang Xu, Yuye Wang, Bin Liao, Zhinan Jiang, Lu Zhao, Zhongcheng Sun, Nan Wu, Tunan Chen, Hua Feng, and Jianquan Yao

Biomed. Opt. Express 10(8), 3953-3962 (2019)  View: HTML | PDF

Identification and investigation of the vibrational properties of crystalline and co-amorphous drugs with Raman and terahertz spectroscopy

Wei Liu, Yu Liu, Jiaoqi Huang, Zhongquan Lin, Xuancheng Pan, Xiaojun Zeng, Marc Lamy de la Chapelle, Yang Zhang, and Weiling Fu

Biomed. Opt. Express 10(8), 4290-4304 (2019)  View: HTML | PDF

Optical characteristics of human skin with hyperpigmentation caused by fluorinated pyrimidine anticancer agent

Takahiro Kono, Nobuaki Imanishi, Keiko Nozawa, Atsuo Takashima, Rajagopalan Uma Maheswari, Hiroki Gonome, and Jun Yamada

Biomed. Opt. Express 10(8), 3747-3759 (2019)  View: HTML | PDF

Quantitative discrimination of biological tissues by micro-elastographic measurement using an epi-illumination Mueller matrix microscope

Pradipta Mukherjee, Tomohisa Horiguchi, Shuhei Shibata, Nathan Hagen, and Yukitoshi Otani

Biomed. Opt. Express 10(8), 3847-3859 (2019)  View: HTML | PDF

Machine learning classification of human joint tissue from diffuse reflectance spectroscopy data

Rajitha Gunaratne, Isaac Monteath, Joshua Goncalves, Raymond Sheh, Charles N Ironside, Michael Kapfer, Richard Chipper, Brett Robertson, Riaz Khan, and Daniel Fick

Biomed. Opt. Express 10(8), 3889-3898 (2019)  View: HTML | PDF

Systematic study of the effect of ultrasound gel on the performances of time-domain diffuse optics and diffuse correlation spectroscopy

Laura Di Sieno, Davide Contini, Giuseppe Lo Presti, Lorenzo Cortese, Tony Mateo, Bogdan Rosinski, Elena Venturini, Pietro Panizza, Mireia Mora, Gloria Aranda, Mattia Squarcia, Andrea Farina, Turgut Durduran, Paola Taroni, Antonio Pifferi, and Alberto Dalla Mora

Biomed. Opt. Express 10(8), 3899-3915 (2019)  View: HTML | PDF

Real-time optical properties and oxygenation imaging using custom parallel processing in the spatial frequency domain

Enagnon Aguénounon, Foudil Dadouche, Wilfried Uhring, and Sylvain Gioux

Biomed. Opt. Express 10(8), 3916-3928 (2019)  View: HTML | PDF

Optical properties of human milk

Colin Veenstra, Anki Lenferink, Wilma Petersen, Wiendelt Steenbergen, and Nienke Bosschaart

Biomed. Opt. Express 10(8), 4059-4074 (2019)  View: HTML | PDF

Validation of diffuse reflectance spectroscopy with magnetic resonance imaging for accurate vertebral bone fat fraction quantification

Akash Swamy, Gustav Burström, Jarich W. Spliethoff, Drazenko Babic, Stefan Ruschke, John M. Racadio, Erik Edström, Adrian Elmi-Terander, Jenny Dankelman, and Benno H. W. Hendriks

Biomed. Opt. Express 10(8), 4316-4328 (2019)  View: HTML | PDF

Directional light-capture efficiency of the foveal and parafoveal photoreceptors at different luminance levels: an experimental and analytical study

Alessandra Carmichael Martins and Brian Vohnsen

Biomed. Opt. Express 10(8), 3760-3772 (2019)  View: HTML | PDF

RAC-CNN: multimodal deep learning based automatic detection and classification of rod and cone photoreceptors in adaptive optics scanning light ophthalmoscope images

David Cunefare, Alison L. Huckenpahler, Emily J. Patterson, Alfredo Dubra, Joseph Carroll, and Sina Farsiu

Biomed. Opt. Express 10(8), 3815-3832 (2019)  View: HTML | PDF

Eye tracking-based estimation and compensation of chromatic offsets for multi-wavelength retinal microstimulation with foveal cone precision

Niklas Domdei, Michael Linden, Jenny L. Reiniger, Frank G. Holz, and Wolf M. Harmening

Biomed. Opt. Express 10(8), 4126-4141 (2019)  View: HTML | PDF

Single-pixel imaging of the retina through scattering media

Rahul Dutta, Silvestre Manzanera, Adrián Gambín-Regadera, Esther Irles, Enrique Tajahuerce, Jesús Lancis, and Pablo Artal

Biomed. Opt. Express 10(8), 4159-4167 (2019)  View: HTML | PDF

Clinical assessment of chromatic aberration in phakic and pseudophakic eyes using a simple autorefractor

María S. Millán, Fidel Vega, Francisco Poyales, and Nuria Garzón

Biomed. Opt. Express 10(8), 4168-4178 (2019)  View: HTML | PDF

Quantitative predictions in small-animal X-ray fluorescence tomography

Kian Shaker, Jakob C. Larsson, and Hans M. Hertz

Biomed. Opt. Express 10(8), 3773-3788 (2019)  View: HTML | PDF