Technical considerations in the Verasonics research ultrasound platform for developing a photoacoustic imaging system

Karl Kratkiewicz, Rayyan Manwar, Yang Zhou, Moein Mozaffarzadeh, and Kamran Avanaki

Biomed. Opt. Express 12(2), 1050-1084 (2021)  View: HTML | PDF

Functional photoacoustic calcium imaging using chlorophosphonazo III in a 3D tumor cell culture

Wei-Wen Liu, Sheng-Hong Chen, and Pai-Chi Li

Biomed. Opt. Express 12(2), 1154-1166 (2021)  View: HTML | PDF

Effect and correction of optode coupling errors in breast imaging using diffuse optical tomography

Shuying Li, Kexin Huang, Menghao Zhang, K. M. Shihab Uddin, and Quing Zhu

Biomed. Opt. Express 12(2), 689-704 (2021)  View: HTML | PDF

In vivo test-driven upgrade of a time domain multi-wavelength optical mammograph

Giulia Maffeis, Edoardo Ferocino, Alberto Dalla Mora, Antonio Pifferi, Rinaldo Cubeddu, and Paola Taroni

Biomed. Opt. Express 12(2), 1105-1122 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Comparative study of autofluorescence in flat and tapered optical fibers towards application in depth-resolved fluorescence lifetime photometry in brain tissue

Marco Bianco, Antonio Balena, Marco Pisanello, Filippo Pisano, Leonardo Sileo, Barbara Spagnolo, Cinzia Montinaro, Bernardo L. Sabatini, Massimo De Vittorio, and Ferruccio Pisanello

Biomed. Opt. Express 12(2), 993-1009 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

RGB-color forward-viewing spectrally encoded endoscope using three orders of diffraction

Mitsuhiro Ikuta, Tzu-Yu Wu, Anderson T. Mach, Alexander Altshuler, Xuri Yan, James H. Houskeeper, Akira Yamamoto, Shumpei Tatsumi, Ken-ichi Iwata, Jiheun Ryu, Adel Zeidan, Guillermo J. Tearney, and Seiji Takeuchi

Biomed. Opt. Express 12(2), 1036-1049 (2021)  View: HTML | PDF

Assessment of the corneal collagen organization after chemical burn using second harmonic generation microscopy

Juan M. Bueno, Francisco J. Ávila, Elvira Lorenzo-Martín, Patricia Gallego-Muñoz, and M. Carmen Martínez-García

Biomed. Opt. Express 12(2), 756-765 (2021)  View: HTML | PDF

Method for assessing the spatiotemporal resolution of structured illumination microscopy (SIM)

Abderrahim Boualam and Christopher J. Rowlands

Biomed. Opt. Express 12(2), 790-801 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Three-dimensional single molecule localization close to the coverslip: a comparison of methods exploiting supercritical angle fluorescence

Philipp Zelger, Lisa Bodner, Martin Offterdinger, Lukas Velas, Gerhard J. Schütz, and Alexander Jesacher

Biomed. Opt. Express 12(2), 802-822 (2021)  View: HTML | PDF

Wavelet-based background and noise subtraction for fluorescence microscopy images

Manuel Hüpfel, Andrei Yu. Kobitski, Weichun Zhang, and G. Ulrich Nienhaus

Biomed. Opt. Express 12(2), 969-980 (2021)  View: HTML | PDF  [Suppl. Mat. (2)]

Three-dimensional characterization of collagen remodeling in cell-seeded collagen scaffolds via polarization second harmonic generation

Dionysios Xydias, Georgios Ziakas, Sotiris Psilodimitrakopoulos, Andreas Lemonis, Eleni Bagli, Theodore Fotsis, Achille Gravanis, Dimitrios S. Tzeranis, and Emmanuel Stratakis

Biomed. Opt. Express 12(2), 1136-1153 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

High-speed multicolor structured illumination microscopy using a hexagonal single mode fiber array

Taylor A. Hinsdale, Sjoerd Stallinga, and Bernd Rieger

Biomed. Opt. Express 12(2), 1181-1194 (2021)  View: HTML | PDF  [Suppl. Mat. (2)]

Effect of A-scan rate and interscan interval on optical coherence angiography

Ting-Hao Chen, Yi-Chun Wu, Ting-Yen Tsai, Chuan-Bor Chueh, Bo-Huei Huang, Yin-Peng Huang, Meng-Tsan Tsai, Yoshiaki Yasuno, and Hsiang-Chieh Lee

Biomed. Opt. Express 12(2), 722-736 (2021)  View: HTML | PDF

Oblique injection depth correction by a two parallel OCT sensor guided handheld SMART injector

Jintaek Im and Cheol Song

Biomed. Opt. Express 12(2), 926-939 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Colon phantoms with cancer lesions for endoscopic characterization with optical coherence tomography

Natalia Zulina, Oscar Caravaca, Guiqiu Liao, Sara Gravelyn, Morgane Schmitt, Keshia Badu, Lucile Heroin, and Michalina J. Gora

Biomed. Opt. Express 12(2), 955-968 (2021)  View: HTML | PDF

Simultaneous 4-phase-shifted full-field optical coherence microscopy

Mantas Žurauskas, Rishyashring R. Iyer, and Stephen A. Boppart

Biomed. Opt. Express 12(2), 981-992 (2021)  View: HTML | PDF

Real-time tool to layer distance estimation for robotic subretinal injection using intraoperative 4D OCT

Michael Sommersperger, Jakob Weiss, M. Ali Nasseri, Peter Gehlbach, Iulian Iordachita, and Nassir Navab

Biomed. Opt. Express 12(2), 1085-1104 (2021)  View: HTML | PDF

Fiber-based SORS-SERDS system and chemometrics for the diagnostics and therapy monitoring of psoriasis inflammatory disease in vivo

Johannes Schleusener, Shuxia Guo, Maxim E. Darvin, Gisela Thiede, Olga Chernavskaia, Florian Knorr, Jürgen Lademann, Jürgen Popp, and Thomas W. Bocklitz

Biomed. Opt. Express 12(2), 1123-1135 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Red and blue light in antitumor photodynamic therapy with chlorin-based photosensitizers: a comparative animal study assisted by optical imaging modalities

Mikhail Kirillin, Daria Kurakina, Aleksandr Khilov, Anna Orlova, Maria Shakhova, Natalia Orlinskaya, and Ekaterina Sergeeva

Biomed. Opt. Express 12(2), 872-892 (2021)  View: HTML | PDF

Anisotropic scattering characteristics of nanoparticles in different morphologies: improving the temperature uniformity of tumors during thermal therapy using forward scattering

Qin Chen, Yatao Ren, Yanmei Yin, and Hong Qi

Biomed. Opt. Express 12(2), 893-906 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Widely-tunable synchronisation-free picosecond laser source for multimodal CARS, SHG, and two-photon microscopy

Duanyang Xu, Sijing Liang, Lin Xu, Konstantinos N. Bourdakos, Peter Johnson, James Read, Jonathan H. V. Price, Sumeet Mahajan, and David J. Richardson

Biomed. Opt. Express 12(2), 1010-1019 (2021)  View: HTML | PDF

Fluorescent bacterial biosensor E. coli/pTdcR-TurboYFP sensitive to terahertz radiation

Danil S. Serdyukov, Tatiana N. Goryachkovskaya, Irina A. Mescheryakova, Sergei A. Kuznetsov, Vasiliy M. Popik, and Sergey E. Peltek

Biomed. Opt. Express 12(2), 705-721 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Malignant and benign thyroid nodule differentiation through the analysis of blood plasma with terahertz spectroscopy

Maria R. Konnikova, Olga P. Cherkasova, Maxim M. Nazarov, Denis A. Vrazhnov, Yuri V. Kistenev, Sergei E. Titov, Elena V. Kopeikina, Sergei P. Shevchenko, and Alexander P. Shkurinov

Biomed. Opt. Express 12(2), 1020-1035 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Sensitivity of frequency-domain optical measurements to brain hemodynamics: simulations and human study of cerebral blood flow during hypercapnia

Thao Pham, Giles Blaney, Angelo Sassaroli, Cristianne Fernandez, and Sergio Fantini

Biomed. Opt. Express 12(2), 766-789 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Visualization of quantitative lipid distribution in mouse liver through near-infrared hyperspectral imaging

Kyohei Okubo, Yuichi Kitagawa, Naoki Hosokawa, Masakazu Umezawa, Masao Kamimura, Tomonori Kamiya, Naoko Ohtani, and Kohei Soga

Biomed. Opt. Express 12(2), 823-835 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Application driven assessment of probe designs for Raman spectroscopy

Isaac J. Pence, Christine M. O’Brien, Laura E. Masson, and Anita Mahadevan-Jansen

Biomed. Opt. Express 12(2), 852-871 (2021)  View: HTML | PDF

Absolute quantification of cerebral tissue oxygen saturation with multidistance broadband NIRS in newborn brain

Zuzana Kovacsova, Gemma Bale, Subhabrata Mitra, Frédéric Lange, and Ilias Tachtsidis

Biomed. Opt. Express 12(2), 907-925 (2021)  View: HTML | PDF

Combined total internal reflection AF spectral-imaging and Raman spectroscopy for fast assessment of surgical margins during breast cancer surgery

Maria Giovanna Lizio, Zhiyu Liao, Dustin W. Shipp, Radu Boitor, Raluca Mihai, James S. Sharp, Matthew Russell, Hazem Khout, Emad A. Rakha, and Ioan Notingher

Biomed. Opt. Express 12(2), 940-954 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Evaluation of the potential eye hazard at visible wavelengths of the supercontinuum generated by an ultrafast NIR laser in water

Xomalin G. Peralta, Joseph E. Clary, Amanda M. Peterson, Gary D. Noojin, Brian J. Lund, Francesco J. Echeverria, and Benjamin A. Rockwell

Biomed. Opt. Express 12(2), 1167-1180 (2021)  View: HTML | PDF

Comparison of confocal and non-confocal split-detection cone photoreceptor imaging

Nripun Sredar, Moataz Razeen, Bartlomiej Kowalski, Joseph Carroll, and Alfredo Dubra

Biomed. Opt. Express 12(2), 737-755 (2021)  View: HTML | PDF