Label-free monitoring of spatiotemporal changes in the stem cell cytoskeletons in time-lapse phase-contrast microscopy

Ching-Fen Jiang and Yu-Man Sun

Biomed. Opt. Express 13(4), 2323-2333 (2022)  View: HTML | PDF  [Suppl. Mat. (4)]

Optimization of photo-biomodulation therapy for wound healing of diabetic foot ulcers in vitro and in vivo

Qianqian Chen, Jichun Yang, Huijuan Yin, Yingxin Li, Haixia Qiu, Ying Gu, Hua Yang, Dong Xiaoxi, Shi Xiafei, Bochen Che, and Hongxiao Li

Biomed. Opt. Express 13(4), 2450-2466 (2022)  View: HTML | PDF  [Suppl. Mat. (1)]

Rational selection of RGB channels for disease classification based on IPPG technology

Ge Xu, Liquan Dong, Jing Yuan, Yuejin Zhao, Ming Liu, Mei Hui, Yuebin Zhao, and Lingqin Kong

Biomed. Opt. Express 13(4), 1820-1833 (2022)  View: HTML | PDF  [Suppl. Mat. (1)]

Regression-based neural network for improving image reconstruction in diffuse optical tomography

Ganesh M. Balasubramaniam and Shlomi Arnon

Biomed. Opt. Express 13(4), 2006-2017 (2022)  View: HTML | PDF

Feature matching for texture-less endoscopy images via superpixel vector field consistency

Shiyuan Liu, Jingfan Fan, Danni Ai, Hong Song, Tianyu Fu, Yongtian Wang, and Jian Yang

Biomed. Opt. Express 13(4), 2247-2265 (2022)  View: HTML | PDF

Convolutional dictionary learning for blind deconvolution of optical coherence tomography images

Junzhe Wang, Brendt Wohlberg, and R. B. A. Adamson

Biomed. Opt. Express 13(4), 1834-1854 (2022)  View: HTML | PDF  [Suppl. Mat. (1)]

Image-to-image translation of label-free molecular vibrational images for a histopathological review using the UNet+/seg-cGAN model

Yunjie He, Jiasong Li, Steven Shen, Kai Liu, Kelvin K. Wong, Tiancheng He, and Stephen T. C. Wong

Biomed. Opt. Express 13(4), 1924-1938 (2022)  View: HTML | PDF

Automatic zoning for retinopathy of prematurity with semi-supervised feature calibration adversarial learning

Yuanyuan Peng, Zhongyue Chen, Weifang Zhu, Fei Shi, Meng Wang, Yi Zhou, Daoman Xiang, Xinjian Chen, and Feng Chen

Biomed. Opt. Express 13(4), 1968-1984 (2022)  View: HTML | PDF

Improving the generalization of glaucoma detection on fundus images via feature alignment between augmented views

Chengfeng Zhou, Juan Ye, Jun Wang, Zhiyong Zhou, Linyan Wang, Kai Jin, Yaofeng Wen, Chun Zhang, and Dahong Qian

Biomed. Opt. Express 13(4), 2018-2034 (2022)  View: HTML | PDF  [Suppl. Mat. (6)]

Surgical scene generation and adversarial networks for physics-based iOCT synthesis

Michael Sommersperger, Alejandro Martin-Gomez, Kristina Mach, Peter Louis Gehlbach, M. Ali Nasseri, Iulian Iordachita, and Nassir Navab

Biomed. Opt. Express 13(4), 2414-2430 (2022)  View: HTML | PDF

Diamond Raman laser and Yb fiber amplifier for in vivo multiphoton fluorescence microscopy

Shaun A. Engelmann, Annie Zhou, Ahmed M. Hassan, Michael R. Williamson, Jeremy W. Jarrett, Evan P. Perillo, Alankrit Tomar, David J. Spence, Theresa A. Jones, and Andrew K. Dunn

Biomed. Opt. Express 13(4), 1888-1898 (2022)  View: HTML | PDF  [Suppl. Mat. (2)]

Axial motion estimation and correction for simultaneous multi-plane two-photon calcium imaging

Andres Flores-Valle and Johannes D. Seelig

Biomed. Opt. Express 13(4), 2035-2049 (2022)  View: HTML | PDF  [Suppl. Mat. (1)]

High-resolution 3D Fourier ptychographic reconstruction using a hemispherical illumination source with multiplexed-coded strategy

Minglu Sun, Lina Shao, Jinrui Zhang, Youqiang Zhu, Peilin Wu, Yukun Wang, Zhihui Diao, QuanQuan Mu, Dayu Li, Hongda Wang, and Li Xuan

Biomed. Opt. Express 13(4), 2050-2067 (2022)  View: HTML | PDF

Identification of DAPI-stained normal, inflammatory, and carcinoma hepatic cells based on hyperspectral microscopy

Sifan Lin, Ze Ke, Kunxing Liu, Siqi Zhu, Zhen Li, Hao Yin, and Zhenqiang Chen

Biomed. Opt. Express 13(4), 2082-2090 (2022)  View: HTML | PDF

Accurate evaluation of the treatment effects of immunotherapy on subcutaneous ovarian cancer in mice with nonlinear optical imaging and algorithmic analysis

Shiqi Wang, Zewei Zhao, Jiajun Xie, Sheng Ren, Shiyao Tang, Fangrui Lin, Junle Qu, and Liwei Liu

Biomed. Opt. Express 13(4), 2266-2277 (2022)  View: HTML | PDF

Co-localized line-field confocal optical coherence tomography and confocal Raman microspectroscopy for three-dimensional high-resolution morphological and molecular characterization of skin tissues ex vivo

Léna Waszczuk, Jonas Ogien, Jean-Luc Perrot, and Arnaud Dubois

Biomed. Opt. Express 13(4), 2467-2487 (2022)  View: HTML | PDF  [Suppl. Mat. (1)]

Generalized figure of merit for plasmonic dip measurement-based surface plasmon resonance sensors

Treesukon Treebupachatsakul, Apivitch Boosamalee, Kamejira Chaithatwanitch, and Suejit Pechprasarn

Biomed. Opt. Express 13(4), 1784-1800 (2022)  View: HTML | PDF

Ultrahigh resolution spectral-domain optical coherence tomography using the 1000–1600 nm spectral band

Liane Bernstein, Antoine Ramier, Jiamin Wu, Vera D. Aiello, Marie J. Béland, Charles P. Lin, and Seok-Hyun Yun

Biomed. Opt. Express 13(4), 1939-1947 (2022)  View: HTML | PDF  [Suppl. Mat. (4)]

In vivo assessment of inflammatory bowel disease in rats with ultrahigh-resolution colonoscopic OCT

Wu Yuan, Yan Feng, Defu Chen, Payam Gharibani, Jiande D. Z. Chen, Huimin Yu, and Xingde Li

Biomed. Opt. Express 13(4), 2091-2102 (2022)  View: HTML | PDF  [Suppl. Mat. (1)]

Light-adapted flicker optoretinograms captured with a spatio-temporal optical coherence-tomography (STOC-T) system

Sławomir Tomczewski, Piotr Węgrzyn, Dawid Borycki, Egidijus Auksorius, Maciej Wojtkowski, and Andrea Curatolo

Biomed. Opt. Express 13(4), 2186-2201 (2022)  View: HTML | PDF  [Suppl. Mat. (1)]

Non-destructive characterization of adult zebrafish models using Jones matrix optical coherence tomography

Antonia Lichtenegger, Pradipta Mukherjee, Lida Zhu, Rion Morishita, Kiriko Tomita, Daisuke Oida, Konrad Leskovar, Ibrahim Abd El-Sadek, Shuichi Makita, Stefanie Kirchberger, Martin Distel, Bernhard Baumann, and Yoshiaki Yasuno

Biomed. Opt. Express 13(4), 2202-2223 (2022)  View: HTML | PDF

Analysis of strain estimation methods in phase-sensitive compression optical coherence elastography

Jiayue Li, Ewelina Pijewska, Qi Fang, Maciej Szkulmowski, and Brendan F. Kennedy

Biomed. Opt. Express 13(4), 2224-2246 (2022)  View: HTML | PDF

Local Burr distribution estimator for speckle statistics

Gary R. Ge, Jannick P. Rolland, and Kevin J. Parker

Biomed. Opt. Express 13(4), 2334-2345 (2022)  View: HTML | PDF

Brain white matter morphological structure correlation with its optical properties estimated from optical coherence tomography (OCT) data

Alexander A. Moiseev, Ksenia A. Achkasova, Elena B. Kiseleva, Konstantin S. Yashin, Arseniy L. Potapov, Evgenia L. Bederina, Sergey S. Kuznetsov, Evgeny P. Sherstnev, Dmitry V. Shabanov, Grigory V. Gelikonov, Yuliya V. Ostrovskaya, and Natalia D. Gladkova

Biomed. Opt. Express 13(4), 2393-2413 (2022)  View: HTML | PDF

Vector of motion measurements in the living cochlea using a 3D OCT vibrometry system

Wihan Kim, Derek Liu, Sangmin Kim, Kumara Ratnayake, Frank Macias-Escriva, Scott Mattison, John S. Oghalai, and Brian E. Applegate

Biomed. Opt. Express 13(4), 2542-2553 (2022)  View: HTML | PDF  [Suppl. Mat. (1)]

Rapid detection of hysteromyoma and cervical cancer based on serum surface-enhanced Raman spectroscopy and a support vector machine

Xiangxiang Zheng, Guohua Wu, Jing Wang, Longfei Yin, and Xiaoyi Lv

Biomed. Opt. Express 13(4), 1912-1923 (2022)  View: HTML | PDF

Noninvasive assessment of liver function reserve with fluorescent dosimetry of indocyanine green

Pei-Chun Wu, Lun-Zhang Guo, Shan Yu, Ning Zeng, Yu-Cheng Liu, Jia Yu, Zhiming Zhang, Ke Lu, Liangyu Sun, Chunfei Wang, Yu-Han Chang, Yin-Lin Lu, Yu-Fang Shen, Sheng Tai, Yueh-Hsun Chuang, Ja-An Annie Ho, Kai-Wen Huang, Yao-Ming Wu, and Tzu-Ming Liu

Biomed. Opt. Express 13(4), 1995-2005 (2022)  View: HTML | PDF  [Suppl. Mat. (1)]

Label-free detection of breast cancer cells using a functionalized tilted fiber grating

Xiaoyong Chen, Pin Xu, Wenwei Lin, Jin Jiang, Hang Qu, Xuehao Hu, Jinghua Sun, and Yukun Cui

Biomed. Opt. Express 13(4), 2117-2129 (2022)  View: HTML | PDF

Hybrid confocal Raman endomicroscopy for morpho-chemical tissue characterization

Conor C. Horgan, Magnus Jensen, Ciro Chiappini, Tom Vercauteren, Richard Cook, and Mads S. Bergholt

Biomed. Opt. Express 13(4), 2278-2285 (2022)  View: HTML | PDF  [Suppl. Mat. (1)]

Fiber-laser platform for precision brain surgery

Nitesh Katta, Arnoldo D. Estrada, Austin B. McErloy, and Thomas E. Milner

Biomed. Opt. Express 13(4), 1985-1994 (2022)  View: HTML | PDF

UV surface disinfection in a wearable drug delivery device

Adam Zrehen, Uri Hili, Noam Weil, Ori Ben-David, Andrei Yosef, and Boaz Eitan

Biomed. Opt. Express 13(4), 2144-2155 (2022)  View: HTML | PDF

Respiratory and heart rate monitoring using an FBG 3D-printed wearable system

Cátia Tavares, Cátia Leitão, Daniela Lo Presti, M. F. Domingues, Nélia Alberto, Hugo Silva, and Paulo Antunes

Biomed. Opt. Express 13(4), 2299-2311 (2022)  View: HTML | PDF

Multi-scale laser speckle contrast imaging of microcirculatory vasoreactivity

Blaire Lee, Olga Sosnovtseva, Charlotte M. Sørensen, and Dmitry D. Postnov

Biomed. Opt. Express 13(4), 2312-2322 (2022)  View: HTML | PDF  [Suppl. Mat. (1)]

Blue-LIRIC in the rabbit cornea: efficacy, tissue effects, and repetition rate scaling

Ruiting Huang, Dan Yu, Daniel Savage, Kaitlin Wozniak, Len Zheleznyak, Wayne H. Knox, and Krystel R. Huxlin

Biomed. Opt. Express 13(4), 2346-2363 (2022)  View: HTML | PDF

Cherenkov light emission in molecular radiation therapy of the thyroid and its application to dosimetry

Jigar Dubal, Pedro Arce, Christopher South, and Lucia Florescu

Biomed. Opt. Express 13(4), 2431-2449 (2022)  View: HTML | PDF

Deep neural network classification of in vivo burn injuries with different etiologies using terahertz time-domain spectral imaging

Omar B. Osman, Zachery B. Harris, Mahmoud E. Khani, Juin W. Zhou, Andrew Chen, Adam J. Singer, and M. Hassan Arbab

Biomed. Opt. Express 13(4), 1855-1868 (2022)  View: HTML | PDF

Label-free study on the effect of a bioactive constituent on glioma cells in vitro using terahertz ATR spectroscopy

Yunsheng Liao, Mingkun Zhang, Mingjie Tang, Ligang Chen, Xueqin Li, Zhongdong Liu, and Huabin Wang

Biomed. Opt. Express 13(4), 2380-2392 (2022)  View: HTML | PDF

Lock-in functional near-infrared spectroscopy for measurement of the haemodynamic brain response

Stanislaw Wojtkiewicz, Karolina Bejm, and Adam Liebert

Biomed. Opt. Express 13(4), 1869-1887 (2022)  View: HTML | PDF  [Suppl. Mat. (4)]

Transient absorption spectroscopy and imaging of redox in muscle mitochondria

Erkang Wang, Luke A. Whitcomb, Adam J. Chicco, and Jesse W. Wilson

Biomed. Opt. Express 13(4), 2103-2116 (2022)  View: HTML | PDF  [Suppl. Mat. (1)]

Optimized spectral filter design enables more accurate estimation of oxygen saturation in spectral imaging

Dale J. Waterhouse and Danail Stoyanov

Biomed. Opt. Express 13(4), 2156-2173 (2022)  View: HTML | PDF  [Suppl. Mat. (1)]

Quantitative chemical sensing of drugs in scattering media with Bessel beam Raman spectroscopy

Nan Wang, Feng Ren, Li Li, Haoyu Wang, Lin Wang, Qi Zeng, Yali Song, Tingting Zeng, Shouping Zhu, and Xueli Chen

Biomed. Opt. Express 13(4), 2488-2502 (2022)  View: HTML | PDF  [Suppl. Mat. (1)]

Cancer detection from stained biopsies using high-speed spectral imaging

Eugene Brozgol, Pramod Kumar, Daniela Necula, Irena Bronshtein-Berger, Moshe Lindner, Shlomi Medalion, Lee Twito, Yotam Shapira, Helena Gondra, Iris Barshack, and Yuval Garini

Biomed. Opt. Express 13(4), 2503-2515 (2022)  View: HTML | PDF  [Suppl. Mat. (1)]

Theoretical investigation of photon partial pathlengths in multilayered turbid media

Héctor A. García, Demián A. Vera, María. V. Waks Serra, Guido R. Baez, Daniela I. Iriarte, and Juan A. Pomarico

Biomed. Opt. Express 13(4), 2516-2529 (2022)  View: HTML | PDF  [Suppl. Mat. (1)]

Femtosecond Er-doped fiber laser source tunable from 872 to 1075 nm for two-photon vision studies in humans

Dorota Stachowiak, Marcin Marzejon, Jakub Bogusławski, Zbigniew Łaszczych, Katarzyna Komar, Maciej Wojtkowski, and Grzegorz Soboń

Biomed. Opt. Express 13(4), 1899-1911 (2022)  View: HTML | PDF  [Suppl. Mat. (1)]

Effect of decentration, tilt and rotation on the optical quality of various toric intraocular lens designs: a numerical and experimental study

Jesús Pérez-Gracia, Jorge Ares, Francisco J. Ávila, and Laura Remón

Biomed. Opt. Express 13(4), 1948-1967 (2022)  View: HTML | PDF

Intraocular scatter compensation with spatial light amplitude modulation for improved vision in simulated cataractous eyes

Spozmai Panezai, Alfonso Jiménez-Villar, Alba M. Paniagua Diaz, Augusto Arias, Grzegorz Gondek, Silvestre Manzanera, Pablo Artal, and Ireneusz Grulkowski

Biomed. Opt. Express 13(4), 2174-2185 (2022)  View: HTML | PDF