Quantitative characterization of bovine serum albumin thin-films using terahertz spectroscopy and machine learning methods

Yiwen Sun, Pengju Du, Xingxing Lu, Pengfei Xie, Zhengfang Qian, Shuting Fan, and Zexuan Zhu

Biomed. Opt. Express 9(7), 2917-2929 (2018)  View: HTML | PDF

Pilot study of freshly excised breast tissue response in the 300 – 600 GHz range

Quentin Cassar, Amel Al-Ibadi, Laven Mavarani, Philipp Hillger, Janusz Grzyb, Gaëtan MacGrogan, Thomas Zimmer, Ullrich R. Pfeiffer, Jean-Paul Guillet, and Patrick Mounaix

Biomed. Opt. Express 9(7), 2930-2942 (2018)  View: HTML | PDF

Image reconstruction in fluorescence molecular tomography with sparsity-initialized maximum-likelihood expectation maximization

Yansong Zhu, Abhinav K. Jha, Dean F. Wong, and Arman Rahmim

Biomed. Opt. Express 9(7), 3106-3121 (2018)  View: HTML | PDF

Weighting function effects in a direct regularization method for image-guided near-infrared spectral tomography of breast cancer

Jinchao Feng, Shudong Jiang, Brian W. Pogue, and Keith Paulsen

Biomed. Opt. Express 9(7), 3266-3283 (2018)  View: HTML | PDF

Simultaneous arteriole and venule segmentation with domain-specific loss function on a new public database

Xiayu Xu, Rendong Wang, Peilin Lv, Bin Gao, Chan Li, Zhiqiang Tian, Tao Tan, and Feng Xu

Biomed. Opt. Express 9(7), 3153-3166 (2018)  View: HTML | PDF

Solving Fourier ptychographic imaging problems via neural network modeling and TensorFlow

Shaowei Jiang, Kaikai Guo, Jun Liao, and Guoan Zheng

Biomed. Opt. Express 9(7), 3306-3319 (2018)  View: HTML | PDF  [Suppl. Mat. (1)]

Super-multiplexed fluorescence microscopy via photostability contrast

Antony Orth, Richik N. Ghosh, Emma R. Wilson, Timothy Doughney, Hannah Brown, Philipp Reineck, Jeremy G. Thompson, and Brant C. Gibson

Biomed. Opt. Express 9(7), 2943-2954 (2018)  View: HTML | PDF

Millisecond cellular labelling in situ with two-photon photoconversion

Sheldon J. J. Kwok, Yongjae Jo, Harvey H. Lin, Myunghwan Choi, and Seok-Hyun Yun

Biomed. Opt. Express 9(7), 3067-3077 (2018)  View: HTML | PDF  [Suppl. Mat. (6)]

On-chip light-sheet fluorescence imaging flow cytometry at a high flow speed of 1 m/s

Taichi Miura, Hideharu Mikami, Akihiro Isozaki, Takuro Ito, Yasuyuki Ozeki, and Keisuke Goda

Biomed. Opt. Express 9(7), 3424-3433 (2018)  View: HTML | PDF

Visualization of drug distribution of a topical minocycline gel in human facial skin

Sinyoung Jeong, Maiko Hermsmeier, Sam Osseiran, Akira Yamamoto, Usha Nagavarapu, Kin F. Chan, and Conor L. Evans

Biomed. Opt. Express 9(7), 3434-3448 (2018)  View: HTML | PDF

Real-time visualization of two-photon fluorescence lifetime imaging microscopy using a wavelength-tunable femtosecond pulsed laser

Jiheun Ryu, Ungyo Kang, Jayul Kim, Hyunjun Kim, Jue Hyung Kang, Hyunjin Kim, Dae Kyung Sohn, Jae-heon Jeong, Hongki Yoo, and Bomi Gweon

Biomed. Opt. Express 9(7), 3449-3463 (2018)  View: HTML | PDF  [Suppl. Mat. (1)]

Pixel-wise segmentation of severely pathologic retinal pigment epithelium and choroidal stroma using multi-contrast Jones matrix optical coherence tomography

Shinnosuke Azuma, Shuichi Makita, Arata Miyazawa, Yasushi Ikuno, Masahiro Miura, and Yoshiaki Yasuno

Biomed. Opt. Express 9(7), 2955-2973 (2018)  View: HTML | PDF

Effect of patch size and network architecture on a convolutional neural network approach for automatic segmentation of OCT retinal layers

Jared Hamwood, David Alonso-Caneiro, Scott A. Read, Stephen J. Vincent, and Michael J. Collins

Biomed. Opt. Express 9(7), 3049-3066 (2018)  View: HTML | PDF

Deep learning for the segmentation of preserved photoreceptors on en face optical coherence tomography in two inherited retinal diseases

Acner Camino, Zhuo Wang, Jie Wang, Mark E. Pennesi, Paul Yang, David Huang, Dengwang Li, and Yali Jia

Biomed. Opt. Express 9(7), 3092-3105 (2018)  View: HTML | PDF

Realistic simulation and experiment reveals the importance of scatterer microstructure in optical coherence tomography image formation

Paweł Ossowski, Andrea Curatolo, David D. Sampson, and Peter R. T. Munro

Biomed. Opt. Express 9(7), 3122-3136 (2018)  View: HTML | PDF

Automatic quantification of choroidal neovascularization lesion area on OCT angiography based on density cell-like P systems with active membranes

Jie Xue, Acner Camino, Steven T. Bailey, Xiyu Liu, Dengwang Li, and Yali Jia

Biomed. Opt. Express 9(7), 3208-3219 (2018)  View: HTML | PDF

Machine-learning based segmentation of the optic nerve head using multi-contrast Jones matrix optical coherence tomography with semi-automatic training dataset generation

Deepa Kasaragod, Shuichi Makita, Young-Joo Hong, and Yoshiaki Yasuno

Biomed. Opt. Express 9(7), 3220-3243 (2018)  View: HTML | PDF

DRUNET: a dilated-residual U-Net deep learning network to segment optic nerve head tissues in optical coherence tomography images

Sripad Krishna Devalla, Prajwal K. Renukanand, Bharathwaj K. Sreedhar, Giridhar Subramanian, Liang Zhang, Shamira Perera, Jean-Martial Mari, Khai Sing Chin, Tin A. Tun, Nicholas G. Strouthidis, Tin Aung, Alexandre H. Thiéry, and Michaël J. A. Girard

Biomed. Opt. Express 9(7), 3244-3265 (2018)  View: HTML | PDF

Temporally and spatially adaptive Doppler analysis for robust handheld optical coherence elastography

Xuan Liu, Farzana R. Zaki, Haokun Wu, Chizhong Wang, and Yahui Wang

Biomed. Opt. Express 9(7), 3335-3353 (2018)  View: HTML | PDF  [Suppl. Mat. (3)]

Fiber-based visible and near infrared optical coherence tomography (vnOCT) enables quantitative elastic light scattering spectroscopy in human retina

Weiye Song, Libo Zhou, Sui Zhang, Steven Ness, Manishi Desai, and Ji Yi

Biomed. Opt. Express 9(7), 3464-3480 (2018)  View: HTML | PDF  [Suppl. Mat. (2)]

On the dysfunctional hemoglobins and cyanosis connection: practical implications for the clinical detection and differentiation of methemoglobinemia and sulfhemoglobinemia

Stephen W. Askew and Gladimir V. G. Baranoski

Biomed. Opt. Express 9(7), 3284-3305 (2018)  View: HTML | PDF

Effect of spatial light distribution on the thermal response of vascular tissue

Van Gia Truong, Van Nam Tran, Jieun Hwang, and Hyun Wook Kang

Biomed. Opt. Express 9(7), 3037-3048 (2018)  View: HTML | PDF

Segmentation of vessel structures from photoacoustic images with reliability assessment

Pasi Raumonen and Tanja Tarvainen

Biomed. Opt. Express 9(7), 2887-2904 (2018)  View: HTML | PDF  [Suppl. Mat. (2)]

Quantitative diagnosis of tissue microstructure with wide-field high spatial frequency domain imaging

Weihao Lin, Bixin Zeng, Zili Cao, Xinlin Chen, Kaiyan Yang, and Min Xu

Biomed. Opt. Express 9(7), 2905-2916 (2018)  View: HTML | PDF

Multiwavelength time-resolved near-infrared spectroscopy of the adult head: assessment of intracerebral and extracerebral absorption changes

Anna Gerega, Daniel Milej, Wojciech Weigl, Michal Kacprzak, and Adam Liebert

Biomed. Opt. Express 9(7), 2974-2993 (2018)  View: HTML | PDF

Comparison of source localization techniques in diffuse optical tomography for fNIRS application using a realistic head model

Julie Tremblay, Eduardo Martínez-Montes, Phetsamone Vannasing, Dang K. Nguyen, Mohamad Sawan, Franco Lepore, and Anne Gallagher

Biomed. Opt. Express 9(7), 2994-3016 (2018)  View: HTML | PDF

Decoding cortical brain states from widefield calcium imaging data using visibility graph

Li Zhu, Christian R. Lee, David J. Margolis, and Laleh Najafizadeh

Biomed. Opt. Express 9(7), 3017-3036 (2018)  View: HTML | PDF  [Suppl. Mat. (2)]

Fundus autofluorescence beyond lipofuscin: lesson learned from ex vivo fluorescence lifetime imaging in porcine eyes

Martin Hammer, Lydia Sauer, Matthias Klemm, Sven Peters, Rowena Schultz, and Jens Haueisen

Biomed. Opt. Express 9(7), 3078-3091 (2018)  View: HTML | PDF

Prenatal detection of thalassemia by cell-free fetal DNA (cffDNA) in maternal plasma using surface enhanced Raman spectroscopy combined with PCR

Xiaozhou Li, Tianyue Yang, Caesar Siqi Li, Lili Jin, Hong Lou, and Youtao Song

Biomed. Opt. Express 9(7), 3167-3176 (2018)  View: HTML | PDF

Prediction of the anti-glioma therapeutic effects of temozolomide through in vivo molecular imaging of MMP expression

Li Li, Yang Du, Dehui Xiang, Liang Chen, Zhifeng Shi, Jie Tian, and Xinjian Chen

Biomed. Opt. Express 9(7), 3193-3207 (2018)  View: HTML | PDF

New fluorescent compounds produced by femtosecond laser surgery in biological tissues: the mechanisms

Zhongya Qin, Qiqi Sun, Yue Lin, Sicong He, Xuesong Li, Congping Chen, Wanjie Wu, Yi Luo, and Jianan Y. Qu

Biomed. Opt. Express 9(7), 3373-3390 (2018)  View: HTML | PDF

Real-time localization of the parathyroid gland in surgical field using Raspberry Pi during thyroidectomy: a preliminary report

Yikeun Kim, Sung Won Kim, Kang Dae Lee, and Yeh-chan Ahn

Biomed. Opt. Express 9(7), 3391-3398 (2018)  View: HTML | PDF

Near-simultaneous quantification of glucose uptake, mitochondrial membrane potential, and vascular parameters in murine flank tumors using quantitative diffuse reflectance and fluorescence spectroscopy

Caigang Zhu, Hannah L. Martin, Brian T. Crouch, Amy F. Martinez, Martin Li, Gregory M. Palmer, Mark W. Dewhirst, and Nimmi Ramanujam

Biomed. Opt. Express 9(7), 3399-3412 (2018)  View: HTML | PDF

Assessment of the radiotherapy effect for nasopharyngeal cancer using plasma surface-enhanced Raman spectroscopy technology

Qiong Wu, Sufang Qiu, Yun Yu, Weiwei Chen, Huijing Lin, Duo Lin, Shangyuan Feng, and Rong Chen

Biomed. Opt. Express 9(7), 3413-3423 (2018)  View: HTML | PDF

Glare-free retinal imaging using a portable light field fundus camera

Douglas W. Palmer, Thomas Coppin, Krishan Rana, Donald G. Dansereau, Marwan Suheimat, Michelle Maynard, David A. Atchison, Jonathan Roberts, Ross Crawford, and Anjali Jaiprakash

Biomed. Opt. Express 9(7), 3178-3192 (2018)  View: HTML | PDF

Selective retina therapy enhanced with optical coherence tomography for dosimetry control and monitoring: a proof of concept study

Daniel Kaufmann, Christian Burri, Patrik Arnold, Volker M. Koch, Christoph Meier, Boris Považay, and Jörn Justiz

Biomed. Opt. Express 9(7), 3320-3334 (2018)  View: HTML | PDF

Visualization of laser tattoo removal treatment effects in a mouse model by two-photon microscopy: erratum

Won Hyuk Jang, Yeoreum Yoon, Wonjoong Kim, Soonjae Kwon, Seunghun Lee, Duke Song, Jong Woon Choi, and Ki Hean Kim

Biomed. Opt. Express 9(7), 3177-3177 (2018)  View: HTML | PDF