Abstract

We have developed a compact, multimodal instrument for simultaneous acquisition of en face quasi-confocal fundus images and adaptive-optics (AO) spectral-domain optical coherence tomography (SDOCT) cross-sectional images. The optical system including all AO and SDOCT components occupies a $60\times 60\mathrm{cm}$ breadboard that can be readily transported for clinical applications. The AO component combines a Hartmann–Shack wavefront sensor and a microelectromechanical systems-based deformable mirror to sense and correct ocular aberrations at $15\mathrm{Hz}$ with a maximum stroke of $4\mu \mathrm{m}$. A broadband superluminescent diode source provides $4\mu \mathrm{m}$ depth resolution for SDOCT imaging. In human volunteer testing, we observed up to an $8\mathrm{dB}$ increase in OCT signal and a corresponding lateral resolution of $<10\mu \mathrm{m}$ as a result of AO correction.

© 2007 Optical Society of America

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