Abstract

Multimodal imaging (MMI) is a new imaging technique that combines an electrophysiological test (multifocal electroretinogram) with an optical coherence tomography ophthalmoscope. MMI allows the two technologies to operate simultaneously yet independently to provide accurate correlation of macular structure and function at multiple sites. Preliminary work with MMI in patients with macular holes showed that functional deficits existed beyond the geographical area of structural alterations and that macular hole size did not always correlate with the severity of functional loss. Functional information may therefore be important when assessing prognosis in these patients. We envisage that MMI may prove a useful new tool in the assessment of many macular pathologies.

© 2007 Optical Society of America

Imaging localized retinal dysfunction with the multifocal electroretinogram

Marcus A. Bearse and Erich E. Sutter
J. Opt. Soc. Am. A 13(3) 634-640 (1996)

Large-field-of-view, modular, stabilized, adaptive-optics-based scanning laser ophthalmoscope

Stephen A. Burns, Remy Tumbar, Ann E. Elsner, Daniel Ferguson, and Daniel X. Hammer
J. Opt. Soc. Am. A 24(5) 1313-1326 (2007)

Gaze-contingent display for retinal function testing by scanning laser ophthalmoscope

Manfred MacKeben and Alexander Gofen
J. Opt. Soc. Am. A 24(5) 1402-1410 (2007)

Decline of photopic multifocal electroretinogram responses with age is due primarily to preretinal optical factors

Brad Fortune and Chris A. Johnson
J. Opt. Soc. Am. A 19(1) 173-184 (2002)

Adaptive optics-optical coherence tomography: optimizing visualization of microscopic retinal structures in three dimensions

Robert J. Zawadzki, Stacey S. Choi, Steven M. Jones, Scot S. Oliver, and John S. Werner
J. Opt. Soc. Am. A 24(5) 1373-1383 (2007)