Relating wavefront error to visual acuity in pre- and post-LASIK eyes: a comparison of methods

Edward Dehoog; Robert Van Dine; Lindsay Fitzgerald-Dehoog; Jim Schwiegerling

doi:10.1364/JOSAA.37.000192

Journal of the Optical Society of America A
Vol. 37,
Issue 2,
pp. 192-198
(2020)
•https://doi.org/10.1364/JOSAA.37.000192

Relating wavefront error to visual acuity in pre- and post-LASIK eyes: a comparison of methods

Edward Dehoog, Robert Van Dine, Lindsay Fitzgerald-Dehoog, and Jim Schwiegerling

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Edward Dehoog, Robert Van Dine, Lindsay Fitzgerald-Dehoog, and Jim Schwiegerling, "Relating wavefront error to visual acuity in pre- and post-LASIK eyes: a comparison of methods," J. Opt. Soc. Am. A 37, 192-198 (2020)

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Abstract

Contrast threshold and visual Strehl ratio methods are used to predict visual acuity from wavefront error for a sample population of pre- and post-LASIK patients. Relative error (in logMAR) between predicted and measured visual acuity values are computed for each method and compared using paired t-tests. Differences in aberration data between pre- and post-LASIK eyes are then evaluated. The visual acuity prediction using visual Strehl proved to be more accurate for pre-LASIK patients than contrast threshold. However, both methods are comparable for post-LASIK patients.

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Days Since Procedure	0	7	30	90	180	360
Mean	0.0065	0.0947	0.0596	0.0371	0.0629	0.0744
Standard deviation	0.09636	0.1526	0.1773	0.1363	0.1780	0.1646
Max	0.4	0.7	1	0.5	0.8	0.7
Min	$- 0.22$	$- 0.2$	$- 0.3$	$- 0.3$	$- 0.22$	$- 0.3$
Number of eyes	152	155	144	126	102	128

Test Comparison	Degrees of Freedom	Test Statistic	$P$ Value
CT tangential versus VS error	151	29.6011	$< 2.2 e - 16$
CT sagittal versus VS error	151	28.6157	$< 2.2 e - 16$
CT tangential versus CT sagittal error	151	1.3651	0.1742

Aberration	Pre-LASIK Mean	Post-LASIK Mean	T	$P$ Value
Defocus	0.00397	0.000521	−20.7	$< 0.0001$
Astigmatism	0.000861	0.000588	−3.29	0.0012
Coma	0.000284	0.000341	1.54	0.1258
Spherical	0.0000732	0.000347	11.33	$< 0.0001$
RMS WFE	0.00858	0.00253	−22.54	$< 0.0001$

	Parameter	Estimate	Standard Error	T	$P$ Value	$R$
Pre-LASIK	intercept	0.0389	0.007	5.93	$< 0.0001$	0.35
	astigmatism	14.2	5.65	2.52	0.0127
	spherical	−43.9	21.4	−2.05	0.0420
	logMAR	0.408	0.0521	7.84	$< 0.0001$
Post-LASIK	intercept	0.194	0.00744	25.0	$< 0.0001$	0.92
	RMS WFE	−18.6	2.90	−6.40	$< 0.0001$
	logMAR	0.904	0.0221	40.9	0.0019

	Parameter	Estimate	Standard Error	$T$	$P$ Value	$R$
Pre-LASIK	intercept	0.668	0.106	6.31	$< 0.0001$	0.33
	RMS WFE	98.6	11.4	8.68	$< 0.0001$
Post-LASIK	intercept	0.0832	0.0268	3.23	0.0015	0.28
	RMS WFE	32.2	10.0	3.20	0.0017
	logMAR	0.398	0.0765	5.20	$< 0.0001$

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Journal of the Optical Society of America A