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Three dimensional OCT images from retina and skin

Adrian Gh. Podoleanu, John A. Rogers, David A. Jackson, and Shane Dunne

Open Access Open Access

Abstract

We demonstrate the functionality of an en-face optical coherence tomography (OCT) system with images from the retina and skin. En-face images collected at different depths are subsequently used to reconstruct a 3D volume of the tissue. The reconstruction allows software inferred OCT longitudinal images at any transversal position in the stack. The position in depth in the stack before creating longitudinal OCT images is also adjustable, offering a valuable guidance tool for exploring the 3D volume of the tissue. This is illustrated by Quick time movies showing either depth or lateral exploration along one of two possible different directions in the stack of transversal OCT images. Sufficient accuracy of the volume rendered is obtained in 20 seconds when the system operates at 2 frames a second. The system, equipped with the 3D rendering feature acts as a valuable diagnostic tool allowing “peeling off” of transversal and longitudinal biologic material to investigate different internal features.

©2000 Optical Society of America

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Supplementary Material (4)

Media 1: MOV (2363 KB)     
Media 2: MOV (1246 KB)     
Media 3: MOV (1513 KB)     
Media 4: MOV (2352 KB)     

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Figures (5)
Fig. 1.
Fig. 1. Three modes of operation of the three scanners in an OCT system.

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Fig. 2.
Fig. 2. (2.37 MB) Movie of three-dimensional in vivo optic nerve. The volume is explored from the retinal nerve fiber layer to the retinal pigment epithelium, along the optic axis. Volume size: 3 mm×3 mm×1.1 mm (air).

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Fig. 3.
Fig. 3. (1.25 MB) (Y,Z) longitudinal slices in the stack of transversal OCT images from in vivo optic nerve at different X positions. Volume size: 3 mm×3 mm×1.1 mm (air).

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Fig. 4.
Fig. 4. (1.5 MB) Movie of three-dimensional in vivo finger tip. The volume is explored from the outside to the inside of the finger, along the optic axis. Volume size: 5 mm×4 mm×1 mm (air).

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Fig. 5.
Fig. 5. (2.3 MB) (Y,Z) longitudinal slices in the stack of transversal OCT images from in vivo finger tip at different X positions. Volume size: 5 mm×4 mm×1 mm (air).

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