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Compact, low-cost Ti:Al2O3 laser for in vivo ultrahigh-resolution optical coherence tomography

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Abstract

A compact, low-cost, prismless Ti:Al2O3 laser with 176-nm bandwidth (FWHM) and 20-mW output power was developed. Ultrahigh-resolution ophthalmic optical coherence tomography (OCT) ex vivo imaging in an animal model with 1.2µm axial resolution and in vivo imaging in patients with macular pathologies with 3µm axial resolution were demonstrated. Owing to the pump laser, this light source significantly reduces the cost of broadband OCT systems. Furthermore, the source has great potential for clinical application of spectroscopic and ultrahigh-resolution OCT because of its small footprint (500 mm×180 mm including the pump laser), user friendliness, stability, and reproducibility.

© 2003 Optical Society of America

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