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Wide dynamic range detection of bidirectional flow in Doppler optical coherence tomography using a two-dimensional Kasai estimator

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Abstract

We demonstrate extended axial flow velocity detection range in a time-domain Doppler optical coherence tomography (DOCT) system using a modified Kasai velocity estimator with computations in both the axial and transverse directions. For a DOCT system with an 8kHz rapid-scanning optical delay line, bidirectional flow experiments showed a maximum detectable speed of >56cms using the axial Kasai estimator without the occurrence of aliasing, while the transverse Kasai estimator preserved the 7μms minimum detectable velocity to slow flow. By using a combination of transverse Kasai and axial Kasai estimators, the velocity detection dynamic range was over 100dB. Through a fiber-optic endoscopic catheter, in vivo M-mode transesophageal imaging of the pulsatile blood flow in rat aorta was demonstrated, for what is for the first time to our knowledge, with measured peak systolic blood flow velocity of >1ms, while maintaining good sensitivity to detect aortic wall motion at <2mms, using this 2D Kasai technique.

© 2007 Optical Society of America

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