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Three-dimensional coregistered optical coherence tomography and line-scanning fluorescence laminar optical tomography

Shuai Yuan, Qian Li, James Jiang, Alex Cable, and Yu Chen

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Abstract

We present a combined optical coherence tomography (OCT) and line-scanning fluorescence laminar optical tomography (FLOT) system. This hybrid system enables coregistered structural and molecular imaging in 3D with 10–100 μm resolution and millimeter-scale imaging depth. Experimental results on a capillary phantom with fluorescence dye Cy5.5 using an OCT/FLOT imaging system have been demonstrated.

© 2009 Optical Society of America

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