Abstract

We present a combined optical coherence tomography (OCT) and line-scanning fluorescence laminar optical tomography (FLOT) system. This hybrid system enables coregistered structural and molecular imaging in 3D with 10–100 μm resolution and millimeter-scale imaging depth. Experimental results on a capillary phantom with fluorescence dye Cy5.5 using an OCT/FLOT imaging system have been demonstrated.

© 2009 Optical Society of America

Full Article  |  PDF Article
More Like This
High-dynamic-range fluorescence laminar optical tomography (HDR-FLOT)

Qinggong Tang, Yi Liu, Vassiliy Tsytsarev, Jonathan Lin, Bohan Wang, Udayakumar Kanniyappan, Zhifang Li, and Yu Chen
Biomed. Opt. Express 8(4) 2124-2137 (2017)

Depth-resolved imaging of colon tumor using optical coherence tomography and fluorescence laminar optical tomography

Qinggong Tang, Jianting Wang, Aaron Frank, Jonathan Lin, Zhifang Li, Chao-wei Chen, Lily Jin, Tongtong Wu, Bruce D. Greenwald, Hiroshi Mashimo, and Yu Chen
Biomed. Opt. Express 7(12) 5218-5232 (2016)

Three-dimensional fluorescence optical tomography in small-animal imaging using simultaneous positron-emission-tomography priors

Changqing Li, Guobao Wang, Jinyi Qi, and Simon R. Cherry
Opt. Lett. 34(19) 2933-2935 (2009)

View More...

References

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Supplementary Material (1)

Media 1: AVI (1782 KB)     

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Figures (3)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Metrics