Abstract
We used two-dimensional laser Raman scattering and elastic light scattering to analyze mixture driven particle formation in the supercritical antisolvent process. Using only one excitation laser, the partial density of the antisolvent , the composition of the solvent/antisolvent mixture, and the occurrence of particle formation can be analyzed simultaneously. Thus, all main parameters that influence the process of particle formation and, sub sequently, the desired properties of the produced powder are accessible.
© 2010 Optical Society of America
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