Expand this Topic clickable element to expand a topic
Skip to content
Optica Publishing Group

Optimized speckle variance OCT imaging of microvasculature

Not Accessible

Your library or personal account may give you access

Abstract

We optimize speckle variance optical coherence tomography (svOCT) imaging of microvasculature in high and low bulk tissue motion scenarios. To achieve a significant level of image contrast, frame rates must be optimized such that tissue displacement between frames is less than the beam radius. We demonstrate that higher accuracy estimates of speckle variance can enhance the detection of capillaries. These findings are illustrated in vivo by imaging the dorsal window chamber model (low bulk motion). We also show svOCT imaging of the nonstabilized finger (high bulk motion), using optimized imaging parameters, demonstrating better vessel detection than Doppler OCT.

© 2010 Optical Society of America

Full Article  |  PDF Article
More Like This
Spectroscopic-speckle variance OCT for microvasculature detection and analysis

Xuan Liu, Kang Zhang, Yong Huang, and Jin U. Kang
Biomed. Opt. Express 2(11) 2995-3009 (2011)

Speckle variance detection of microvasculature using swept-source optical coherence tomography

Adrian Mariampillai, Beau A. Standish, Eduardo H. Moriyama, Mamta Khurana, Nigel R. Munce, Michael K. K. Leung, James Jiang, Alex Cable, Brian C. Wilson, I. Alex Vitkin, and Victor X. D. Yang
Opt. Lett. 33(13) 1530-1532 (2008)

Quantifying tissue microvasculature with speckle variance optical coherence tomography

Leigh Conroy, Ralph S. DaCosta, and I. Alex Vitkin
Opt. Lett. 37(15) 3180-3182 (2012)

References

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Supplementary Material (2)

Media 1: AVI (3693 KB)     
Media 2: AVI (1797 KB)     

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Figures (4)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Equations (2)

You do not have subscription access to this journal. Equations are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Metrics

Select as filters


Select Topics Cancel
© Copyright 2022 | Optica Publishing Group. All Rights Reserved