Expand this Topic clickable element to expand a topic
Skip to content
Optica Publishing Group

Characterization of the self-rotational motion of stored red blood cells by using optically-induced electrokinetics

Not Accessible

Your library or personal account may give you access

Abstract

We report a label-free approach toward the object of characterizing the self-rotational motions of red blood cells (RBCs) during storage under the optically-induced electrokinetics-based microfluidics mechanism. A theoretical analysis of the transmembrane potential across RBCs was performed getting a threshold voltage for keeping cellular biological integrity. Then, by investigation of the self-rotational behaviors of the individual RBCs in larger population, the RBCs that were stored more than three weeks statistically showed the distinctive self-rotational speed. Results verified that the self-rotational biomarkers of the RBCs could be used to label-free reckon the qualities of the stored RBCs in this kind of microfluidics chip. This finding may be further developed as a new criterion to real-time and label-free monitoring of the banked blood qualities, thereby diminishing the blood transfusion venture.

© 2016 Optical Society of America

Full Article  |  PDF Article
More Like This
Label-free characterization of different kinds of cells using optoelectrokinetic-based microfluidics

Wenfeng Liang, Xieliu Yang, Junhai Wang, Yuechao Wang, Hemin Zhang, Wenguang Yang, and Lianqing Liu
Opt. Lett. 45(8) 2454-2457 (2020)

Measurement of red blood cell deformability during morphological changes using rotating-glass-plate-based scanning optical tweezers

Rui Liu, Meng Shao, Zeyu Ke, Changxu Li, Fengya Lu, Min-Cheng Zhong, Yuxin Mao, Xunbin Wei, Zhensheng Zhong, and Jinhua Zhou
Biomed. Opt. Express 14(9) 4979-4989 (2023)

Label-free optical sensor based on red blood cells laser tweezers Raman spectroscopy analysis for ABO blood typing

Duo Lin, Zuci Zheng, Qiwen Wang, Hao Huang, Zufang Huang, Yun Yu, Sufang Qiu, Cuncheng Wen, Min Cheng, and Shangyuan Feng
Opt. Express 24(21) 24750-24759 (2016)

Supplementary Material (1)

NameDescription
Visualization 1: MP4 (14697 KB)      Complete experimental details of Fig. 3

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Figures (5)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Equations (1)

You do not have subscription access to this journal. Equations are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Select as filters


Select Topics Cancel
© Copyright 2024 | Optica Publishing Group. All Rights Reserved